An interview with Professor Robert J. Lefkowitz, M.D. Interview by Vicki Glaser.
Abstract
Robert J. Lefkowitz, M.D., is James B. Duke Professor of Medicine and Professor of
Biochemistry at the Duke University Medical Center. He has been an Investigator of
the Howard Hughes Medical Institute since 1976. Dr. Lefkowitz received a Bachelor's
degree from Columbia College and an M.D. degree from Columbia University College of
Physicians and Surgeons. After serving an internship and one year of general medical
residency at the College of Physicians and Surgeons, he served as a Clinical and Research
Associate with Drs. Jesse Roth and Ira Pastan at the National Institutes of Health.
He then completed his medical residency and research and clinical training in cardiovascular
disease at the Massachusetts General Hospital, Boston. During this time, he continued
his research in the laboratories of Dr. Edgar Haber and was a teaching fellow at Harvard
Medical School. On completing his training, he was appointed Associate Professor of
Medicine and Assistant Professor of Biochemistry at the Duke University Medical Center.
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http://hdl.handle.net/10161/7798Published Version (Please cite this version)
10.1089/15406580360545044Publication Info
(2003). An interview with Professor Robert J. Lefkowitz, M.D. Interview by Vicki Glaser. Assay Drug Dev Technol, 1(2). pp. 233-238. 10.1089/15406580360545044. Retrieved from http://hdl.handle.net/10161/7798.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Robert J. Lefkowitz
James B. Duke Professor of Medicine
The focus of work in this laboratory is on the elucidation of the molecular properties
and regulatory mechanisms controlling the function of G protein-coupled receptors.
As model systems we utilize the so called adrenergic receptors for adrenaline and
related molecules. The goal is to learn the general principles of signal transduction
from the outside to the inside of the cell which are involved in systems as diverse
as sensory perception, neuro- transmitter and hormonal signaling. Stud
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