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Diseased G protein-coupled receptors.

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Date
1993-11
Authors
Lefkowitz, RJ
Premont, RT
Repository Usage Stats
205
views
227
downloads
Type
Journal article
Subject
GTP-Binding Proteins
Humans
Mutation
Receptors, Corticotropin
Permalink
https://hdl.handle.net/10161/7845
Published Version (Please cite this version)
10.1172/JCI116806
Publication Info
Lefkowitz, RJ; & Premont, RT (1993). Diseased G protein-coupled receptors. J Clin Invest, 92(5). pp. 2089. 10.1172/JCI116806. Retrieved from https://hdl.handle.net/10161/7845.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Lefkowitz

Robert J. Lefkowitz

The Chancellor's Distinguished Professor of Medicine
Dr. Lefkowitz’s memoir, A Funny Thing Happened on the Way to Stockholm, recounts his early career as a cardiologist and his transition to biochemistry, which led to his Nobel Prize win. Robert J. Lefkowitz, M.D. is James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at the Duke University Medical Center. He has been an Investigator of the
Premont

Richard Thomas Premont

Associate Professor in Medicine
Critical physiological events throughout the body are controlled by extracellular signals from neurotransmitters and hormones acting on cell surface receptors. Receptors transduce these signals to alter intracellular metabolism and cellular responsiveness through heterotrimeric G protein/second messenger pathways or through small GTP-binding protein/protein kinase cascades. The mechanisms that control the responsiveness of target organ G protein-coupled receptors include receptor ph
Alphabetical list of authors with Scholars@Duke profiles.
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