Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways.
Repository Usage Stats
Receptor, Epidermal Growth Factor
Receptors, Adrenergic, beta
Receptors, Cell Surface
Published Version (Please cite this version)10.1210/edrv-9-1-38
Publication InfoBenovic, JL; Caron, MG; Lefkowitz, Robert J; & Sibley, DR (1988). Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways. Endocr Rev, 9(1). pp. 38-56. 10.1210/edrv-9-1-38. Retrieved from https://hdl.handle.net/10161/7872.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
More InfoShow full item record
James B. Duke Distinguished Professor of Medicine
The focus of work in this laboratory is on the elucidation of the molecular properties and regulatory mechanisms controlling the function of G protein-coupled receptors. As model systems we utilize the so called adrenergic receptors for adrenaline and related molecules. The goal is to learn the general principles of signal transduction from the outside to the inside of the cell which are involved in systems as diverse as sensory perception, neuro- transmitter and hormonal signaling. Stud
Showing items related by title, author, creator, and subject.
Achiriloaie, M; Albanesi, JP; Claing, A; Lefkowitz, Robert J; Perry, SJ; Premont, Richard Thomas; Walker, JK (Proc Natl Acad Sci U S A, 2000-02-01)Recently, we identified a GTPase-activating protein for the ADP ribosylation factor family of small GTP-binding proteins that we call GIT1. This protein initially was identified as an interacting partner for the G protein-coupled ...
Diversé-Pierluissi, M; Drazner, Mark H; Dyer, SL; Freedman, NJ; Lefkowitz, Robert J; Oppermann, M; Peppel, Karsten C (Proc Natl Acad Sci U S A, 1996-07-23)Guanine nucleotide-binding regulatory protein (G protein)-coupled receptor kinases (GRKs) constitute a family of serine/threonine kinases that play a major role in the agonist-induced phosphorylation and desensitization ...
Hagiwara, M; Jarvis, Erich David; Sakaguchi, H; Wada, K (J Comp Neurol, 2004-08-09)Learned vocalization, the substrate for human language, is a rare trait. It is found in three distantly related groups of birds-parrots, hummingbirds, and songbirds. These three groups contain cerebral vocal nuclei for learned ...