Setting an agenda for comparative effectiveness systematic reviews in CKD care.
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Systematic reviews comparing the effectiveness of strategies to prevent, detect, and treat chronic kidney disease are needed to inform patient care. We engaged stakeholders in the chronic kidney disease community to prioritize topics for future comparative effectiveness research systematic reviews. We developed a preliminary list of suggested topics and stakeholders refined and ranked topics based on their importance. Among 46 topics identified, stakeholders nominated 18 as 'high' priority. Most pertained to strategies to slow disease progression, including: (a) treat proteinuria, (b) improve access to care, (c) treat hypertension, (d) use health information technology, and (e) implement dietary strategies. Most (15 of 18) topics had been previously studied with two or more randomized controlled trials, indicating feasibility of rigorous systematic reviews. Chronic kidney disease topics rated by stakeholders as 'high priority' are varied in scope and may lead to quality systematic reviews impacting practice and policy.
SubjectComparative Effectiveness Research
Health Services Needs and Demand
Health Services Research
Outcome Assessment (Health Care)
Renal Insufficiency, Chronic
Published Version (Please cite this version)10.1186/1471-2369-13-74
Publication InfoBoulware, Ebony; Choi, MJ; Crawford, PR; Crews, DC; Doggett, D; Fadrowski, JJ; ... Segal, JB (2012). Setting an agenda for comparative effectiveness systematic reviews in CKD care. BMC Nephrol, 13. pp. 74. 10.1186/1471-2369-13-74. Retrieved from https://hdl.handle.net/10161/8326.
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Eleanor Easley Chair in the School of Medicine
Dr. Boulware is the Eleanor Easley Chair in the School of Medicine, Chief of the Division of General Internal Medicine in the Department of Medicine, Vice Dean for Translational Science, and Associate Vice Chancellor for Translational Research at Duke University. She is a general internist and clinical epidemiologist. She studies mechanisms to improve the quality and equity of health care and health outcomes for individuals and populations affected by chronic health conditions including kidne