DukeSpace: Recent submissions
Now showing items 1-20 of 17972
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Antifungal drugs: Special problems treating central nervous system infections
(Journal of Fungi, 2019-12-01)© 2019 by the author. Licensee MDPI, Basel, Switzerland. Treating fungal infections in the central nervous system (CNS) remains a challenge despite the availability of new antifungal agents. Therapy is limited by ... -
Evaluation of a Standardized Cardiac Athletic Screening for National Collegiate Athletic Association (NCAA) Athletes.
(The western journal of emergency medicine, 2019-08-14)INTRODUCTION:Sudden cardiac death is a rare cause of death in young athletes. Current screening techniques include history and physical exam (H and P), with or without an electrocardiogram (ECG). Adding point of care cardiac ... -
Multi-version Indexing in Flash-based Key-Value Stores
(2019-12-02) -
Multi-Objective GIS Analysis for Avoided Conversion Carbon Credits and Biodiversity Conservation
(2019-12-06)This project develops a unique methodology in identifying individual tax parcels in North Carolina as possible locations for generating avoided conversion carbon offset credits, as well as including co-benefits such as ecological ... -
Deep multiscale model learning
(Journal of Computational Physics, 2019-11) -
Artificial intelligence for art investigation: Meeting the challenge of separating x-ray images of the Ghent Altarpiece.
(Science advances, 2019-08-30)X-ray images of polyptych wings, or other artworks painted on both sides of their support, contain in one image content from both paintings, making them difficult for experts to "read." To improve the utility of these x-ray ... -
Increasing Physician Assistant Students' Team Communication Skills and Confidence Throughout Clinical Training.
(The journal of physician assistant education : the official journal of the Physician Assistant Education Association, 2019-10-25)PURPOSE:An intervention was designed to increase physician assistant students' team communication skills using the Situation-Background-Assessment-Recommendation (SBAR) tool. METHODS:A variety of learning activities were ... -
Obstacles to social mobility in India—and the way forward
(Current History, 2019-04-01) -
Association between preoperative respiratory support and outcomes in paediatric cardiac surgery.
(Cardiology in the young, 2019-11-27)BACKGROUND:Preoperative mechanical ventilation is associated with morbidity and mortality following CHD surgery, but prior studies lack a comprehensive analysis of how preoperative respiratory support mode and timing affects ... -
Feasibility assessment of invigorating grassrooTs primary healthcare for prevention and management of cardiometabolic diseases in resource-limited settings in China, Kenya, Nepal, Vietnam (the FAITH study): rationale and design.
(Global health research and policy, 2019-01)Background:Cardiometabolic diseases are the leading cause of death and disability in many low- and middle-income countries. As the already severe burden from these conditions continues to increase in low- and middle-income ... -
Correction: Wearable Digital Sensors to Identify Risks of Postpartum Depression and Personalize Psychological Treatment for Adolescent Mothers: Protocol for a Mixed Methods Exploratory Study in Rural Nepal.
(JMIR research protocols, 2019-10-30)[This corrects the article DOI: 10.2196/14734.]. -
Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans.
(Frontiers in Cellular and Infection Microbiology, 2019-01)The Mkt1-Pbp1 complex promotes mating-type switching by regulating the translation of HO mRNA in Saccharomyces cerevisiae. Here, we performed in vivo immunoprecipitation assays and mass spectrometry analyses in the human ... -
Prevalence of left ventricular diastolic dysfunction by cardiac magnetic resonance imaging in thalassemia major patients with normal left ventricular systolic function.
(BMC cardiovascular disorders, 2019-11-06)BACKGROUND:The leading cause of mortality of thalassemia major patients is iron overload cardiomyopathy. Early diagnosis with searching for left ventricular diastolic dysfunction before the systolic dysfunction ensued might ... -
Embryo microinjection of the lecithotrophic sea urchin Heliocidaris erythrogramma.
(Journal of biological methods, 2019-01)Microinjection is a common embryological technique used for many types of experiments, including lineage tracing, manipulating gene expression, or genome editing. Injectable reagents include mRNA overexpression, mis-expression, ... -
Neurocognitive Effects of Combined Electroconvulsive Therapy (ECT) and Venlafaxine in Geriatric Depression: Phase 1 of the PRIDE Study.
(The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019-10-12)OBJECTIVE:There is limited information regarding the tolerability of electroconvulsive therapy (ECT) combined with pharmacotherapy in elderly adults with major depressive disorder (MDD). Addressing this gap, we report acute ... -
Longitudinal associations between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults : BMI change and the risks of colorectal cancer incidence and mortality.
(BMC cancer, 2019-11-11)BACKGROUND:It remains controversial whether weight change could influence the risks of colorectal cancer (CRC) and mortality. This study aimed to quantify the associations between full-spectrum changes in body mass index ... -
Novel genetic variants in HDAC2 and PPARGC1A of the CREB-binding protein pathway predict survival of non-small-cell lung cancer.
(Molecular carcinogenesis, 2019-11-12)The CREB-binding protein (CBP) pathway plays an important role in transcription and activity of acetyltransferase that acetylates lysine residues of histones and nonhistone proteins. In the present study, we hypothesized ... -
MEK1/2 as a Therapeutic Target in Sickle Cell Disease.
(International journal of blood research and disorders, 2019-01)Identification of novel therapeutic targets has improved diagnostics and treatment of many diseases. Many innovative treatment strategies have been developed based on the newly identified biomarkers and key molecules. Most ... -
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): are neurologists feeling more comfortable to RESTART antiplatelet?
(Annals of translational medicine, 2019-09)
