DukeSpace: Recent submissions
Now showing items 1-20 of 27552
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Cellular communication among smooth muscle cells: The role of membrane potential via connexins.
(Journal of theoretical biology, 2023-11)Communication via action potentials among neurons has been extensively studied. However, effective communication without action potentials is ubiquitous in biological systems, yet it has received much less attention ... -
Assessing the nonlinear association of environmental factors with antibiotic resistance genes (ARGs) in the Yangtze River Mouth, China.
(Scientific reports, 2023-11)The emergence of antibacterial resistance (ABR) is an urgent and complex public health challenge worldwide. Antibiotic resistant genes (ARGs) are considered as a new pollutant by the WHO because of their wide distribution ... -
A 15-year consolidated overview of data in over 6000 patients from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
(Orphanet journal of rare diseases, 2023-11)<h4>Background</h4>Transthyretin amyloidosis (ATTR amyloidosis) is a progressive, multisystemic, life-threatening disease resulting from the deposition of variant or wild-type (ATTRwt amyloidosis) transthyretin amyloid fibrils ... -
Improved AlphaFold modeling with implicit experimental information.
(Nature methods, 2022-11)Machine-learning prediction algorithms such as AlphaFold and RoseTTAFold can create remarkably accurate protein models, but these models usually have some regions that are predicted with low confidence or poor accuracy. ... -
Accelerating crystal structure determination with iterative AlphaFold prediction.
(Acta crystallographica. Section D, Structural biology, 2023-03)Experimental structure determination can be accelerated with artificial intelligence (AI)-based structure-prediction methods such as AlphaFold. Here, an automatic procedure requiring only sequence information and crystallographic ... -
The importance of residue-level filtering and the Top2018 best-parts dataset of high-quality protein residues.
(Protein science : a publication of the Protein Society, 2022-01)We have curated a high-quality, "best-parts" reference dataset of about 3 million protein residues in about 15,000 PDB-format coordinate files, each containing only residues with good electron density support for a physically ... -
Metabolic factors associated with incident fracture among older adults with type 2 diabetes mellitus: a nested case-control study.
(Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2023-07)Older adults with type 2 diabetes mellitus have an increased risk of fracture despite a paradoxically higher average bone mineral density. This study identified additional markers of fracture risk in this at-risk population. ... -
Nightshift imposes irregular lifestyle behaviors in police academy trainees.
(Sleep advances : a journal of the Sleep Research Society, 2023-01)<h4>Study objective</h4>Shiftwork increases risk for numerous chronic diseases, which is hypothesized to be linked to disruption of circadian timing of lifestyle behaviors. However, empirical data on timing of lifestyle ... -
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease and Transverse Myelitis Probably Associated With SARS-CoV-2 mRNA Vaccines: Two Case Reports.
(The Neurohospitalist, 2022-07)Post-vaccination CNS demyelinating syndromes have been reported with a variety of vaccines including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. We report a case of myelin oligodendrocyte ... -
Subthreshold opioid use disorder prevention (STOP) trial: a cluster randomized clinical trial: study design and methods.
(Addiction science & clinical practice, 2023-11)<h4>Background</h4>Preventing progression to moderate or severe opioid use disorder (OUD) among people who exhibit risky opioid use behavior that does not meet criteria for treatment with opioid agonists or antagonists ... -
Health Consequences of Thymus Removal in Adults.
(The New England journal of medicine, 2023-11) -
A multilevel mHealth intervention boosts adherence to hydroxyurea in individuals with sickle cell disease.
(Blood advances, 2023-09)Hydroxyurea reduces sickle cell disease (SCD) complications, but medication adherence is low. We tested two mobile health (mHealth) interventions targeting determinants of low adherence among patients (InCharge Health) and ... -
Microendoscopic Ultrasound-Guided Percutaneous Tracheostomy (MUGPT): A Case Series Describing a Novel Technique for Performing Percutaneous Tracheostomy.
(Case Rep Crit Care, 2023)A percutaneous tracheostomy is a common surgical procedure done in intensive care. Several different techniques have been described. Recently, the addition of bronchoscopy or ultrasound has been advocated to decrease the ... -
“Selection, planning and execution of minimally invasive surgery in adult spinal deformity correction”
(Seminars in Spine Surgery, 2023-01-01)Minimally invasive surgery (MIS) for correction of adult spinal deformity was developed to address the high rate of medical and surgical complications rate in open surgical treatment of increasingly aging and frail patient ... -
Evolving concepts in pelvic fixation in adult spinal deformity surgery
(Seminars in Spine Surgery, 2023-01-01)Long-segment adult spinal deformity (ASD) constructs carry a high risk of mechanical complications. Pelvic fixation was introduced to improve distal construct mechanics and has since become the standard for long constructs ... -
Greater improvement in Neck Disability Index scores in women after surgery for cervical myelopathy: an analysis of the Quality Outcomes Database.
(Neurosurgical focus, 2023-11)<h4>Objective</h4>There is a high prevalence of cervical myelopathy that requires surgery; as such, it is important to identify how different groups benefit from surgery. The American Association of Neurological Surgeons ... -
Use of supplemental rod constructs in adult spinal deformity surgery
(Seminars in Spine Surgery, 2023-01-01)Operative treatment for adult spinal deformity (ASD) commonly involves long posterior instrumented fusions with primary rods spanning from the base of the construct to the upper instrumented vertebra. Over the past decade, ... -
International Society for the Advancement of Spine Surgery Statement: Restorative Neurostimulation for Chronic Mechanical Low Back Pain Resulting From Neuromuscular Instability
(International Journal of Spine Surgery, 2023-10-30)This International Society for the Advancement of Spine Surgery statement has been generated to respond to growing requests for background, supporting literature and evidence, and proper coding for restorative neurostimulation ... -
The Case for Operative Efficiency in Adult Spinal Deformity Surgery: Impact of Operative Time on Complications, Length of Stay, Alignment, Fusion Rates, and Patient Reported Outcomes.
(Spine, 2023-11)<h4>Study design</h4>Retrospective review of prospectively collected data.<h4>Objective</h4>To analyze the impact of operative room (OR) time in adult spinal deformity (ASD) surgery on patient outcomes.<h4>Background</h4>It ... -
What factors influence surgical decision-making in anterior versus posterior surgery for cervical myelopathy? A QOD analysis.
(Journal of neurosurgery. Spine, 2023-11)<h4>Objective</h4>The aim of this study was to explore the preoperative patient characteristics that affect surgical decision-making when selecting an anterior or posterior operative approach in patients diagnosed with cervical ...
