Medication adherence: A practical measurement selection guide using case studies.

dc.contributor.author

Zullig, Leah L

dc.contributor.author

Mendys, Phil

dc.contributor.author

Bosworth, Hayden B

dc.date.accessioned

2024-01-31T00:46:17Z

dc.date.available

2024-01-31T00:46:17Z

dc.date.issued

2017-07

dc.description.abstract

Objectives

Medication adherence is a complex problem and can be evaluated using a variety of methods. There is no single or perfect strategy to assess adherence. The "best" measure depends on contextual factors. Our objective is to provide a practical, illustrative guide for selecting the most appropriate measure of medication adherence in common contexts.

Methods

We present three case studies - from the perspectives of an academic researcher, health care payer, and clinical care provider - to describe common problems and processes for measuring medication adherence, as well as proposing possible solutions.

Results

The most appropriate measure will depend on the context (tightly controlled clinical trial setting vs. clinical setting), intended purpose (research vs. clinical), available resources (data, personnel, materials, and funding), time (quick screening vs. comprehensive review), and phase of interest (initiation, implementation, or discontinuation). Framing the problem of medication non-adherence and methods for measuring adherence are discussed using three representative case studies.

Conclusions

A simple tool is provided that may help stakeholders interested in medication adherence make decisions regarding the appropriate selection of measures.

Practice implications

A medication adherence measure should be selected through the lens of each situation's unique objectives, resources, and needs.
dc.identifier

S0738-3991(17)30065-4

dc.identifier.issn

0738-3991

dc.identifier.issn

1873-5134

dc.identifier.uri

https://hdl.handle.net/10161/29908

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Patient education and counseling

dc.relation.isversionof

10.1016/j.pec.2017.02.001

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.subject

Humans

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Guidelines as Topic

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Medication Adherence

dc.title

Medication adherence: A practical measurement selection guide using case studies.

dc.type

Journal article

duke.contributor.orcid

Zullig, Leah L|0000-0002-6638-409X

duke.contributor.orcid

Bosworth, Hayden B|0000-0001-6188-9825

pubs.begin-page

1410

pubs.end-page

1414

pubs.issue

7

pubs.organisational-group

Duke

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School of Medicine

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Basic Science Departments

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Clinical Science Departments

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Institutes and Centers

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Medicine

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Psychiatry & Behavioral Sciences

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Medicine, General Internal Medicine

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Duke Cancer Institute

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Duke Clinical Research Institute

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Institutes and Provost's Academic Units

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Center for the Study of Aging and Human Development

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Initiatives

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Duke Science & Society

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Population Health Sciences

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Duke Innovation & Entrepreneurship

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Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

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Duke - Margolis Center For Health Policy

pubs.publication-status

Published

pubs.volume

100

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