A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans
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2012-12-31
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Abstract
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk for suicidality, depression, and functional impairment. We thus conducted a small (N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group. Paroxetine may have promise for subthreshold PTSD.
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Naylor, Jennifer C, Trygve R Dolber, Jennifer L Strauss, Jason D Kilts, Timothy J Strauman, Daniel W Bradford, Steven T Szabo, Nagy A Youssef, et al. (2012). A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans. Psychiatry Research. 10.1016/j.psychres.2012.11.008 Retrieved from https://hdl.handle.net/10161/13846.
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Jennifer C. Naylor
Jennifer Leigh Strauss
Jason David Kilts
Daniel William Bradford
Dr. Bradford's clinical and administrative work, research, and teaching is all in the area of mental health services for individuals with serious mental illnesses, particularly psychotic disorders. Since 2012, he has served as the National Director of Intensive Community Psychosocial Rehabilitation for the Department of Veterans Affairs in the Office of Mental Health. In this role, he is responsible for policy development and oversight of over 170 assertive community treatment-based clinical teams serving approximately 15,000 Veterans annually. In 2020, he was the primary author on the first VA national directive on early episode psychosis and currently co-leads this national initiative. In 2022, he accepted the additional role as the Director of the Psychotic Disorders Program at the VA National Expert Consultation and Specialized Services (NEXCSS) program. This program provides expert consultation evaluations and cognitive behavioral therapy for psychosis to veterans throughout the country.
In his clinical and administrative work at Durham VA Medical Center, he was the founding Division Chief for Psychosocial Rehabilitation and Recovery Services from 2014-2022. In prior years, he was also the founding Director of the Inteprofessional Fellowship for Psychosocial Rehabilitation and Recovery Services (2007-2012) and of the Psychosocial Rehabilitation and Recovery Services (2007-2014). He continues as a clinical psychiatrist and resident supervisor in the Division.
Dr. Bradford is board certified in Psychiatry by the American Board of Psychiatry and Neurology and in Addiction Medicine by the American Board of Preventive Medicine. He is a 2013 recipient of an Exemplary Psychiatrist Award from the National Alliance on Mental Illness (NAMI).
Christine Elizabeth Marx
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