Facets of physical function assessed by patient-reported outcome measures in oncology research.
| dc.contributor.author | Coles, Theresa | |
| dc.contributor.author | Fillipo, Rebecca | |
| dc.contributor.author | Plyler, Kate | |
| dc.contributor.author | Hernandez, Alexy | |
| dc.contributor.author | Henke, Debra M | |
| dc.contributor.author | Arizmendi, Cara | |
| dc.contributor.author | Cantrell, Sarah | |
| dc.contributor.author | Lagoo-Deenadayalan, Sandhya | |
| dc.contributor.author | Rory Goodwin, C | |
| dc.contributor.author | LeBlanc, Thomas W | |
| dc.contributor.author | Horodniceanu, Erica G | |
| dc.contributor.author | Bhatnagar, Vishal | |
| dc.contributor.author | Reeve, Bryce B | |
| dc.contributor.author | Weinfurt, Kevin | |
| dc.date.accessioned | 2024-05-29T17:35:57Z | |
| dc.date.available | 2024-05-29T17:35:57Z | |
| dc.date.issued | 2024-04 | |
| dc.description.abstract | PurposeThe U.S. Food & Drug Administration has identified physical functioning (PF) as a core patient-reported outcome (PRO) in cancer clinical trials. The purpose of this study was to identify PF PRO measures (PROMs) in adult cancer populations and classify the PROMs by content covered (facets of PF) in each measure.MethodsAs part of the Patient Reports of Physical Functioning Study (PROPS) research program, we conducted a targeted literature review to identify PROMs that could be used in clinical trials to evaluate PF from the patient perspective. Next, we convened an advisory panel to conduct a modified, reactive, Delphi study to reach consensus on which PF facets are assessed by PROMs identified in the review. The panel engaged in a "card sort" activity to classify PROM items by PF facets. Consensus was reached when 80% of panel members agreed that at least one facet was being measured by each PROM item.ResultsThe literature review identified 13 PROMs that met inclusion criteria. Eight facets of PF were identified for classification in the Delphi study: ability, completion, difficulty, limitation, quality, frequency, bother, and satisfaction. Through two rounds, the panel documented and classified conceptual approaches for each PRO item presented. The most prevalent PF facets were ability, difficulty, and limitation.ConclusionClassifying PF PROMs by PF facets will promote more consistent communication regarding the aspects of PF represented in each PROM, helping researchers prioritize measures for inclusion in cancer clinical trials. | |
| dc.identifier | 10.1007/s11136-024-03640-0 | |
| dc.identifier.issn | 0962-9343 | |
| dc.identifier.issn | 1573-2649 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Springer Science and Business Media LLC | |
| dc.relation.ispartof | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation | |
| dc.relation.isversionof | 10.1007/s11136-024-03640-0 | |
| dc.rights.uri | ||
| dc.subject | Cancer | |
| dc.subject | Delphi panel | |
| dc.subject | Patient-reported outcomes | |
| dc.subject | Physical function | |
| dc.title | Facets of physical function assessed by patient-reported outcome measures in oncology research. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Coles, Theresa|0000-0003-2941-8999 | |
| duke.contributor.orcid | Fillipo, Rebecca|0000-0003-1467-7971 | |
| duke.contributor.orcid | Cantrell, Sarah|0000-0003-2694-7836 | |
| duke.contributor.orcid | LeBlanc, Thomas W|0000-0002-0546-7895 | |
| duke.contributor.orcid | Reeve, Bryce B|0000-0002-6709-8714 | |
| duke.contributor.orcid | Weinfurt, Kevin|0000-0002-0624-7448 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Trinity College of Arts & Sciences | |
| pubs.organisational-group | Staff | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Biostatistics & Bioinformatics | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Orthopaedic Surgery | |
| pubs.organisational-group | Pediatrics | |
| pubs.organisational-group | Psychiatry & Behavioral Sciences | |
| pubs.organisational-group | Radiation Oncology | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Psychology & Neuroscience | |
| pubs.organisational-group | Duke Clinical Research Institute | |
| pubs.organisational-group | University Initiatives & Academic Support Units | |
| pubs.organisational-group | Initiatives | |
| pubs.organisational-group | Duke Science & Society | |
| pubs.organisational-group | Neurosurgery | |
| pubs.organisational-group | Population Health Sciences | |
| pubs.organisational-group | Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences | |
| pubs.organisational-group | Medicine, Hematologic Malignancies and Cellular Therapy | |
| pubs.organisational-group | Medical Center Library & Archives | |
| pubs.publication-status | Published |
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- Coles - Facets of PF assessed by PROMs in Onc Research - Final Accepted.pdf
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- Coles - Facets of PF - Appendices Accepted.pdf
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