Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation.

dc.contributor.author

Sigmund, Curt D

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Carey, Robert M

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Appel, Lawrence J

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Arnett, Donna K

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Bosworth, Hayden B

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Cushman, William C

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Galis, Zorina S

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Green Parker, Melissa

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Hall, John E

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Harrison, David G

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McDonough, Alicia A

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Nicastro, Holly L

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Oparil, Suzanne

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Osborn, John W

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Raizada, Mohan K

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Wright, Jacqueline D

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Oh, Young S

dc.date.accessioned

2024-01-02T21:08:31Z

dc.date.available

2024-01-02T21:08:31Z

dc.date.issued

2020-04

dc.description.abstract

The National Heart, Lung, and Blood Institute convened a multidisciplinary working group of hypertension researchers on December 6 to 7, 2018, in Bethesda, MD, to share current scientific knowledge in hypertension and to identify barriers to translation of basic into clinical science/trials and implementation of clinical science into clinical care of patients with hypertension. The goals of the working group were (1) to provide an overview of recent discoveries that may be ready for testing in preclinical and clinical studies; (2) to identify gaps in knowledge that impede translation; (3) to highlight the most promising scientific areas in which to pursue translation; (4) to identify key challenges and barriers for moving basic science discoveries into translation, clinical studies, and trials; and (5) to identify roadblocks for effective dissemination and implementation of basic and clinical science in real-world settings. The working group addressed issues that were responsive to many of the objectives of the National Heart, Lung, and Blood Institute Strategic Vision. The working group identified major barriers and opportunities for translating research to improved control of hypertension. This review summarizes the discussion and recommendations of the working group.

dc.identifier.issn

0194-911X

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1524-4563

dc.identifier.uri

https://hdl.handle.net/10161/29657

dc.language

eng

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Ovid Technologies (Wolters Kluwer Health)

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Hypertension (Dallas, Tex. : 1979)

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10.1161/hypertensionaha.119.13887

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.subject

Animals

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Humans

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Hypertension

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Clinical Trials as Topic

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Translational Research, Biomedical

dc.title

Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation.

dc.type

Journal article

duke.contributor.orcid

Bosworth, Hayden B|0000-0001-6188-9825

pubs.begin-page

902

pubs.end-page

917

pubs.issue

4

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Duke

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School of Medicine

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Basic Science Departments

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Clinical Science Departments

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Institutes and Centers

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Medicine

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Psychiatry & Behavioral Sciences

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Medicine, General Internal Medicine

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Duke Cancer Institute

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Duke Clinical Research Institute

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Institutes and Provost's Academic Units

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Center for the Study of Aging and Human Development

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Initiatives

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Duke Science & Society

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Population Health Sciences

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Duke Innovation & Entrepreneurship

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Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

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Duke - Margolis Center For Health Policy

pubs.publication-status

Published

pubs.volume

75

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