Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review.

dc.contributor.author

Kwan, Yu Heng

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Weng, Si Dun

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Loh, Dionne Hui Fang

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Phang, Jie Kie

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Oo, Livia Jia Yi

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Blalock, Dan V

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Chew, Eng Hui

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Yap, Kai Zhen

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Tan, Corrinne Yong Koon

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Yoon, Sungwon

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Fong, Warren

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Østbye, Truls

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Low, Lian Leng

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Bosworth, Hayden Barry

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Thumboo, Julian

dc.date.accessioned

2023-08-09T16:57:36Z

dc.date.available

2023-08-09T16:57:36Z

dc.date.issued

2020-10

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2023-08-09T16:57:36Z

dc.description.abstract

Background

Medication adherence is essential for improving the health outcomes of patients. Various patient-reported outcome measures (PROMs) have been developed to measure medication adherence in patients. However, no study has summarized the psychometric properties of these PROMs to guide selection for use in clinical practice or research.

Objective

This study aims to evaluate the quality of the PROMs used to measure medication adherence.

Methods

This study was guided by the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. Relevant articles were retrieved from the EMBASE, PubMed, Cochrane Library, Web of Science, and CINAHL (Cumulative Index to Nursing and Allied Health Literature) databases. The PROMs were then evaluated based on the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) guidelines.

Results

A total of 121 unique medication adherence PROMs from 214 studies were identified. Hypotheses testing for construct validity and internal consistency were the most frequently assessed measurement properties. PROMs with at least a moderate level of evidence for ≥5 measurement properties include the Adherence Starts with Knowledge 20, Compliance Questionnaire-Rheumatology, General Medication Adherence Scale, Hill-Bone Scale, Immunosuppressant Therapy Barrier Scale, Medication Adherence Reasons Scale (MAR-Scale) revised, 5-item Medication Adherence Rating Scale (MARS-5), 9-item MARS (MARS-9), 4-item Morisky Medication Adherence Scale (MMAS-4), 8-item MMAS (MMAS-8), Self-efficacy for Appropriate Medication Adherence Scale, Satisfaction with Iron Chelation Therapy, Test of Adherence to Inhalers, and questionnaire by Voils. The MAR-Scale revised, MMAS-4, and MMAS-8 have been administered electronically.

Conclusions

This study identified 121 PROMs for medication adherence and provided synthesized evidence for the measurement properties of these PROMs. The findings from this study may assist clinicians and researchers in selecting suitable PROMs to assess medication adherence.
dc.identifier

v22i10e19179

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1439-4456

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1438-8871

dc.identifier.uri

https://hdl.handle.net/10161/28698

dc.language

eng

dc.publisher

JMIR Publications Inc.

dc.relation.ispartof

Journal of medical Internet research

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10.2196/19179

dc.subject

Humans

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Psychometrics

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Medication Adherence

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Surveys and Questionnaires

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Patient Reported Outcome Measures

dc.title

Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review.

dc.type

Journal article

duke.contributor.orcid

Blalock, Dan V|0000-0002-8349-9825

duke.contributor.orcid

Bosworth, Hayden Barry|0000-0001-6188-9825

pubs.begin-page

e19179

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10

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Duke

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School of Medicine

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Staff

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Basic Science Departments

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Clinical Science Departments

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Institutes and Centers

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Family Medicine and Community Health

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Medicine

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Psychiatry & Behavioral Sciences

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Medicine, General Internal Medicine

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Duke Cancer Institute

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Duke Clinical Research Institute

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Institutes and Provost's Academic Units

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University Institutes and Centers

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Duke Global Health Institute

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Center for the Study of Aging and Human Development

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Initiatives

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Duke Science & Society

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Population Health Sciences

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Duke Innovation & Entrepreneurship

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Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

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Duke - Margolis Center For Health Policy

pubs.publication-status

Published

pubs.volume

22

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