Neomorphic ERα Mutations Drive Progression in Breast Cancer and Present a Challenge for New Drug Discovery.
| dc.contributor.author | McDonnell, Donald P | |
| dc.contributor.author | Norris, John D | |
| dc.contributor.author | Chang, Ching-Yi | |
| dc.coverage.spatial | United States | |
| dc.date.accessioned | 2018-03-01T14:35:04Z | |
| dc.date.available | 2018-03-01T14:35:04Z | |
| dc.date.issued | 2018-02-12 | |
| dc.description.abstract | In this issue of Cancer Cell, Jeselsohn et al. dissect the function of several of the most clinically important estrogen receptor alpha mutants associated with endocrine therapy resistance in breast cancer and demonstrate that they manifest disease-relevant neomorphic activities that likely contribute to tumor pathogenesis. | |
| dc.identifier | ||
| dc.identifier | S1535-6108(18)30014-X | |
| dc.identifier.eissn | 1878-3686 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Elsevier BV | |
| dc.relation.ispartof | Cancer Cell | |
| dc.relation.isversionof | 10.1016/j.ccell.2018.01.014 | |
| dc.title | Neomorphic ERα Mutations Drive Progression in Breast Cancer and Present a Challenge for New Drug Discovery. | |
| dc.type | Journal article | |
| duke.contributor.orcid | McDonnell, Donald P|0000-0002-7331-4700 | |
| duke.contributor.orcid | Chang, Ching-Yi|0000-0003-2115-9574 | |
| pubs.author-url | ||
| pubs.begin-page | 153 | |
| pubs.end-page | 155 | |
| pubs.issue | 2 | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Medicine, Endocrinology, Metabolism, and Nutrition | |
| pubs.organisational-group | Pharmacology & Cancer Biology | |
| pubs.organisational-group | School of Medicine | |
| pubs.publication-status | Published | |
| pubs.volume | 33 |
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