Effect of diabetes mellitus on giant cell arteritis.

dc.contributor.author

Abel, Anne S

dc.contributor.author

Yashkin, Arseniy P

dc.contributor.author

Sloan, Frank A

dc.contributor.author

Lee, Michael S

dc.coverage.spatial

United States

dc.date.accessioned

2017-06-05T17:56:28Z

dc.date.available

2017-06-05T17:56:28Z

dc.date.issued

2015-06

dc.description.abstract

BACKGROUND: To determine if Type 2 diabetes mellitus (DM) is protective against giant cell arteritis (GCA) and to estimate the incidence of GCA diagnosis from Medicare claims. METHODS: Medicare 5% claims files from 1991 to 2011 were used to identify beneficiaries diagnosed with DM, but not GCA, within a 3-year ascertainment period. Propensity score matching was used to define a control group of nondiabetics with comparable demographic covariates. Competing risk regression was then used to assess the impact of DM diagnosis on GCA diagnosis. To allow for a 3-year ascertainment period, the analysis sample was limited to beneficiaries older than 68 years at baseline. RESULTS: A total of 151,041 beneficiaries diagnosed with DM were matched to an equal number of controls. Mean study follow-up was 67.75 months. GCA was diagnosed among 1116 beneficiaries with DM (0.73%) vs 465 (0.30%) controls. The risk of receiving a GCA diagnosis among patients with DM was increased by 100% (subhazard ratio, 2.00; 95% confidence interval, 1.78-2.25). The annual incidence of GCA diagnosis among claims for US Medicare beneficiaries older than 68 years old was 93 in 100,000. CONCLUSIONS: A DM diagnosis is not protective against a GCA diagnosis in the Medicare population. Our data suggest that a DM diagnosis increases the risk of GCA diagnosis within 5.7 years for Medicare beneficiaries older than 68 years.

dc.identifier

https://www.ncbi.nlm.nih.gov/pubmed/25602744

dc.identifier.eissn

1536-5166

dc.identifier.uri

https://hdl.handle.net/10161/14807

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

J Neuroophthalmol

dc.relation.isversionof

10.1097/WNO.0000000000000218

dc.subject

Diabetes Mellitus

dc.subject

Female

dc.subject

Giant Cell Arteritis

dc.subject

Humans

dc.subject

Male

dc.subject

Medicare

dc.subject

Retrospective Studies

dc.subject

United States

dc.title

Effect of diabetes mellitus on giant cell arteritis.

dc.type

Journal article

duke.contributor.orcid

Yashkin, Arseniy P|0000-0002-1185-148X

pubs.author-url

https://www.ncbi.nlm.nih.gov/pubmed/25602744

pubs.begin-page

134

pubs.end-page

138

pubs.issue

2

pubs.organisational-group

Center for Child and Family Policy

pubs.organisational-group

Center for Population Health & Aging

pubs.organisational-group

Duke

pubs.organisational-group

Duke Population Research Center

pubs.organisational-group

Duke Population Research Institute

pubs.organisational-group

Economics

pubs.organisational-group

Nursing

pubs.organisational-group

Sanford

pubs.organisational-group

Sanford School of Public Policy

pubs.organisational-group

School of Nursing

pubs.organisational-group

Staff

pubs.organisational-group

Trinity College of Arts & Sciences

pubs.publication-status

Published

pubs.volume

35

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Effect of diabetes mellitus on giant cell arteritis.pdf
Size:
132 KB
Format:
Adobe Portable Document Format