The channel of death.

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2001-11-26

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Abstract

The proapoptotic members of the Bcl-2 family have been proposed to participate in the formation of a channel that releases these apoptogenic factors when mitochondria receive apoptotic signals. A recent study provides the first direct, biophysical measurement of a potentially apoptosis-specific mitochondrial channel, which is regulated by Bcl-2 family members and may play a primary role in the release of the proapoptotic factors.

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10.1083/jcb.200110147

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Degterev, A, M Boyce and J Yuan (2001). The channel of death. The Journal of cell biology, 155(5). pp. 695–698. 10.1083/jcb.200110147 Retrieved from https://hdl.handle.net/10161/19703.

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Boyce

Michael Scott Boyce

Associate Professor of Biochemistry

The Boyce Lab studies mammalian cell signaling through protein glycosylation. For the latest news, project information and publications from our group, please visit our web site at http://www.boycelab.org or follow us on Twitter at https://twitter.com/BoyceLab.


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