Predicting 90-day return to the emergency department in orthopaedic trauma patients in the Southeastern USA: a machine-learning approach.
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2025-01
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Abstract
Introduction
Return-to-acute-care metrics, such as early emergency department (ED) visits, are key indicators of healthcare quality, with ED returns following surgery often considered avoidable and costly events. Proactively identifying patients at high risk of ED return can support quality improvement efforts, allowing interventions to target vulnerable patients. With its predictive capabilities, machine learning (ML) has shown potential in forecasting various clinical outcomes but remains underutilised in orthopaedic trauma. This study uses a random forest model to predict 90-day ED return in orthopaedic trauma patients, aiming to identify high-risk individuals and elucidate risk factors associated with returns. This study hypothesised that a highly accurate model could be developed to predict patients at high risk of ED return within 90 days of surgery.Purpose
To develop and validate an ML model that predicts 90-day ED returns after orthopaedic trauma surgery using input data readily available in the electronic health record.Methods
This is a retrospective model development and validation study. The study used data from a registry that includes information on all orthopaedic surgeries conducted at a level 1 academic medical centre. Patients who underwent orthopaedic trauma between 1 January 2017 and 1 March 2023 were identified using common procedural terminology code. The model used demographic, comorbid and perioperative variables. Return to the ED was captured as a binary outcome. Model performance was evaluated using the area under the receiver operator curve (AUROC).Results
A total of 12 069 patients met the inclusion criteria. Patients were predominantly female (53%) and white (70%), with a median age of 55. The 90-day ED return rate was 14% (table 1). The random forest model identified body mass index, distance from the patient's residence to the hospital, age, length of hospital stay and complexity of procedure (work relative value unit) as significant predictors of ED return, each accounting for greater than 10% of the total importance across all features in the model (table 2). Further, the model displayed strong discrimination of patients returning to the ED (AUROC=0.74) (figure 1).Conclusions
The random forest model demonstrated predictive discrimination of 90-day ED returns. Critical predictors such as patient distance from the hospital suggest considering geographical and socioeconomic factors in postdischarge care planning. Operational factors such as length of stay or complexity of the procedure also predicted return to the ED. The study lays the groundwork for future predictive models in clinical decision-making and healthcare resource utilisation.Level of evidence
Level III, retrospective model development and validation study.Type
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Publication Info
Valan, Bruno, Aaron Therien, Emily Peairs, Solomon Ayehu, Joshua Taylor, Daniel Zeng, Steven Olson, Rachel Reilly, et al. (2025). Predicting 90-day return to the emergency department in orthopaedic trauma patients in the Southeastern USA: a machine-learning approach. Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention. p. ip-2024-045358. 10.1136/ip-2024-045358 Retrieved from https://hdl.handle.net/10161/34845.
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Scholars@Duke
Steven Arthur Olson
As an Orthopedic Surgeon my primary focus of research is joint preservation. My primary clinical interests are Orthopedic Trauma and Hip Reconstruction.
In Orthopedic Trauma my research interests are 1) Basic science investigations of articular fractures with two current animal models in use. 2) Clinical research includes evaluation of techniques to reduce and stabilize articular fractures, as well as management of open fractures.
In the area of Hip Reconstruction my areas of research are 1) Hip Arthroscopy and treatment of hip disorders, and treatment of labral tears in the treatment of hip pain. 2) Periacetabular osteotomy for the treatment of hip dysplasia.
Rachel Mary Reilly
Christian Pean
Dr. Christian Péan is faculty in the Department of Orthopaedic Surgery at the Duke University School of Medicine, where he serves as Executive Director of AI & IT Innovation. He also holds a secondary appointment as core faculty at the Duke‑Margolis Institute for Health Policy. An orthopaedic trauma surgeon, Dr. Péan’s clinical expertise spans fracture care and arthroplasty for fracture care, with a focus on shoulder procedures, total hip replacement for fracture and post‑traumatic hip arthritis, and the management of complex traumatic conditions including proximal humerus fractures, humerus nonunion, periprosthetic fracture fixation, and pelvis/acetabulum reconstruction.
Dr. Péan’s research addresses critical issues in orthopaedic surgery and health policy, with over 80 peer‑reviewed publications across artificial intelligence, public health, ethics, and surgical technique in orthopaedic trauma. His work leverages AI, data science, policy design, and clinical care transformation to address population health and value-based care in musculoskeletal care. A central thread of his scholarship integrates machine learning and large language models into risk prediction and care coordination to improve surgical outcomes. He has led system‑level efforts to screen for social drivers of health and coordinate resources for patients facing housing instability, transportation barriers, and food insecurity. He also develops and implements LLM‑based technologies that improve clinician workflow, and enhance patient engagement—core elements of population health focused, value‑based specialty care. Dr. Péan is active in policy advocacy and population health, with interests in specialty care alternative payment models.
A physician‑innovator, Dr. Péan is the Founder and CEO of RevelAi Health, a health technology company advancing the transition to value‑based care in musculoskeletal health with conversational AI. Built by clinicians and policy experts, RevelAi Health is designed to improve patient outcomes while combating clinician burnout through AI‑enabled care coordination.
Malcolm R DeBaun
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