The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.
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2015-11
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Abstract
By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA index values ≥3.0 had a positive predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease, making a supplemental Western immunoblot potentially unnecessary.
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Lipsett, Susan C, Nira R Pollock, John A Branda, Caroline D Gordon, Catherine R Gordon, Paul M Lantos and Lise E Nigrovic (2015). The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children. Pediatr Infect Dis J, 34(11). pp. 1260–1262. 10.1097/INF.0000000000000858 Retrieved from https://hdl.handle.net/10161/13955.
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Paul Michael Lantos
I am interested in the spatial epidemiology of infectious diseases. My research utilizes geographic information systems (GIS) and geostatistical analyses to understand the spatial and spatiotemporal distribution of diseases, and their relationship with environmental and demographic factors. I currently have active studies evaluating the spatial distribution of numerous domestic and international infectious diseases, including SARS-CoV-2 (COVID-19), cytomegalovirus, influenza, and Lyme disease. Additionally I am interested in maternal-child health, and I have a number of ongoing studies of neighborhood health disparities in obstetrical care and birth outcomes. I am interested in GIS education and have conducted workshops on public health GIS in Mongolia and China.
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