The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.

dc.contributor.author

Lipsett, Susan C

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Pollock, Nira R

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Branda, John A

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Gordon, Caroline D

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Gordon, Catherine R

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Lantos, Paul M

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Nigrovic, Lise E

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United States

dc.date.accessioned

2017-04-06T19:48:15Z

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2017-04-06T19:48:15Z

dc.date.issued

2015-11

dc.description.abstract

By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA index values ≥3.0 had a positive predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease, making a supplemental Western immunoblot potentially unnecessary.

dc.identifier

https://www.ncbi.nlm.nih.gov/pubmed/26222064

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1532-0987

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https://hdl.handle.net/10161/13955

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

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Pediatr Infect Dis J

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10.1097/INF.0000000000000858

dc.subject

Adolescent

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Child

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Cross-Sectional Studies

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Enzyme-Linked Immunosorbent Assay

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Female

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Humans

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Lyme Disease

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Male

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Predictive Value of Tests

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Retrospective Studies

dc.title

The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.

dc.type

Journal article

pubs.author-url

https://www.ncbi.nlm.nih.gov/pubmed/26222064

pubs.begin-page

1260

pubs.end-page

1262

pubs.issue

11

pubs.organisational-group

Clinical Science Departments

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Duke

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Global Health Institute

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Institutes and Provost's Academic Units

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Medicine

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Medicine, Hospitalists

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Pediatrics

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Pediatrics, Infectious Diseases

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School of Medicine

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University Institutes and Centers

pubs.publication-status

Published

pubs.volume

34

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