Prospective Studies of Minimally Invasive Glaucoma Surgeries: Systematic Review and Quality Assessment.

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Glaucoma is a common blinding disease; while there is no cure, effective treatments include medications, laser, and incisional surgery. There is significant interest from patients and doctors to develop safer surgical options throughout the spectrum of disease, to minimize treatment burden in mild glaucoma patients and to minimize risk of complications in patients needing more aggressive treatment. Surgical procedures called Minimally or Micro-Invasive Glaucoma Surgery (MIGS) are growing in popularity. Eighty-seven prospective studies on MIGS were identified and assessed for quality. Most (74%) did not have a control group. Twelve of the highest quality were reviewed. MIGS procedures appeared to have fewer complications, and lowered intraocular pressure, and reduced medication use. Studies were limited by small sample size, narrow spectrum of glaucomatous disease, and/or conflicts of interest. There is a need for high quality, independently funded and performed, comparative studies on the MIGS to help make treatment decisions.





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Rosdahl, Jullia A, and Divakar Gupta (2020). Prospective Studies of Minimally Invasive Glaucoma Surgeries: Systematic Review and Quality Assessment. Clinical ophthalmology (Auckland, N.Z.), 14. pp. 231–243. 10.2147/opth.s239772 Retrieved from

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Jullia Ann Rosdahl

Associate Professor of Ophthalmology

I am a glaucoma specialist at the Duke Eye Center.
My passions are teaching, caring for patients and doctors, and saving retinal ganglion cells.
My research interests include patient education and adherence, medical and surgical education, OCT imaging for glaucoma, and physician wellness.


Divakar Gupta

Associate Professor of Ophthalmology

Divakar Gupta, MD is a board certified, fellowship-trained ophthalmologist specializing in the medical and surgical treatment of glaucoma and cataracts.  He performs both traditional glaucoma surgery such as trabeculectomy and glaucoma tube shunts, as well as cutting-edge Minimally Invasive Glaucoma Surgery (MIGS).  He is trained in the latest surgical techniques of cataract and laser-assisted cataract surgery.  Dr. Gupta also offers premium intraocular lenses for cataract surgery patients interested in astigmatic correction and/or presbyopia correction.

He has a clinical and research interest in early diagnosis of glaucoma and improving treatment outcomes. His research focuses on novel ways to use optical imaging and technology to identify and manage glaucoma.  Dr. Gupta also spends time teaching and lecturing trainees and eye professionals at the Duke Eye Center and in the community.  When he is not working, he spends his time watching Duke Basketball, playing tennis, and enjoys cooking.

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