A challenging case of invasive pulmonary aspergillosis after near-drowning: a case report and literature review.

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Near-drowning, a relatively common event, is often complicated by subsequent pneumonia. While endogenous and exogenous bacteria are typical pathogens, rarely fungi are as well. We report a complicated case of invasive pulmonary aspergillosis in a 30-year-old man after a near-drowning event. We also review the medical literature for similar cases. All cases of invasive pulmonary aspergillosis after near-drowning reported in the literature involve Aspergillus fumigatus. The majority of cases involved submersion in stagnant water after a motor vehicle accident (MVA). Treatment varied considerably, with amphotericin B used in the majority of cases. Morbidity was considerable with prolonged hospitalization occurring in every case, and mortality occurring in fifty percent of the reported cases. Although a rare complication of near-drowning, invasive pulmonary aspergillosis can occur and lead to significant morbidity and mortality. After near-drowning A. fumigatus isolated from the respiratory tract should be assumed to be a true pathogen and treated accordingly.





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Jenks, Jeffrey D, and Michael Preziosi (2015). A challenging case of invasive pulmonary aspergillosis after near-drowning: a case report and literature review. Infectious diseases in clinical practice (Baltimore, Md.), 23(5). pp. 227–230. 10.1097/ipc.0000000000000263 Retrieved from https://hdl.handle.net/10161/28636.

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Jeffrey Daniel Jenks

Adjunct Associate Professor in the Department of Medicine

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