Using a Regent Aortic Valve in a Small Annulus Mitral Position Is a Viable Option.


BACKGROUND:Outcome of mitral valve replacement in extreme scenarios of small mitral annulus with the use of the Regent mechanical aortic valve is not well documented. METHODS:Records were examined in 31 consecutive patients who underwent mitral valve replacement with the use of the aortic Regent valve because of a small mitral annulus. RESULTS:Mean age was 60 ± 14 years. Mitral stenosis or mitral annulus calcification was present in 30 of 31 patients (97%). Concurrent procedures were performed in 17 of 31 patients (55%). Median valve size was 23 mm. Mean mitral gradient coming out of the operating room was 4.2 ± 1.5 mm Hg and at follow-up echocardiogram performed at a median of 32 months after the procedure was 5.8 ± 2.4 mm Hg. CONCLUSIONS:A Regent aortic mechanical valve can be a viable option with a larger orifice area than the regular mechanical mitral valve in a problematic situation of a small mitral valve annulus. Moreover, the pressure gradients over the valve are acceptable intraoperatively and over time.





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Publication Info

Barac, Yaron D, Brittany Zwischenberger, Jacob N Schroder, Mani A Daneshmand, John C Haney, Jeffrey G Gaca, Andrew Wang, Carmelo A Milano, et al. (2018). Using a Regent Aortic Valve in a Small Annulus Mitral Position Is a Viable Option. The Annals of thoracic surgery, 105(4). pp. 1200–1204. 10.1016/j.athoracsur.2017.11.042 Retrieved from

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Brittany Anne Zwischenberger

Assistant Professor of Surgery

Jacob Niall Schroder

Assistant Professor of Surgery

Jeffrey Giles Gaca

Associate Professor of Surgery

Andrew Wang

Professor of Medicine

Structural heart diseases, including valvular heart disease, hemodynamics, infective endocarditis, and hypertrophic cardiomyopathy


Carmelo Alessio Milano

Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery

Donald D. Glower

Professor of Surgery

Current clinical research projects examine the effects of patient characteristics and surgical technique in outcome after minimally invasive cardiac surgery, valve repair and replacement, and coronary artery bypass grafting.
Prior work has examined the role of surgical therapy versus medical therapy in aortic dissection, load-independent means to quantify left and right ventricular function, and management of complex coronary disease.

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