The impact of lumbar alignment targets on mechanical complications after adult lumbar scoliosis surgery.

dc.contributor.author

Dial, Brian L

dc.contributor.author

Hills, Jeffrey M

dc.contributor.author

Smith, Justin S

dc.contributor.author

Sardi, Juan Pablo

dc.contributor.author

Lazaro, Bruno

dc.contributor.author

Shaffrey, Christopher I

dc.contributor.author

Bess, Shay

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Schwab, Frank J

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Lafage, Virginie

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Lafage, Renaud

dc.contributor.author

Kelly, Michael P

dc.contributor.author

Bridwell, Keith H

dc.date.accessioned

2023-06-15T17:29:25Z

dc.date.available

2023-06-15T17:29:25Z

dc.date.issued

2022-06

dc.date.updated

2023-06-15T17:29:25Z

dc.description.abstract

Purpose

The purpose of this study was to determine the discriminatory ability of age-adjusted alignment offset and the global alignment and proportion (GAP) score parameters to predict postoperative mechanical complications.

Methods

Surgical patients from the Adult Symptomatic Lumbar Scoliosis cohort were reviewed at 2 year follow up. Age-adjusted alignment offsets and GAP parameters were calculated for each patient. A series of nonlinear logistic regression models were fit, and the odds of mechanical complications were calculated. The discriminatory ability of the GAP score, GAP score parameters, and age-adjusted alignment offsets were determined plotting receiver operative characteristic (ROC) with the C statistic (AUC).

Results

A total of 165 patients were included. A total of 49 mechanical complications occurred in 41 patients (21 proximal junctional kyphosis and 28 pseudoarthrosis). The GAP score had no discriminatory ability in this cohort. Relative lumbar lordosis 15 degrees greater than ideal lumbar lordosis was associated with greater mechanical complications. A lumbar distribution index of 90% was associated with fewer mechanical complications compared to a lumbar distribution index of 65%. Age-adjusted offset alignment targets had no discriminatory ability to predict mechanical complications.

Conclusion

Radiographic alignment targets using either age-adjusted alignment target offset or GAP score parameters had minimal ability to predict mechanical complications in isolation. Mechanical complications following adult spinal deformity surgery are complex, and patient factors play a critical role. Clinical trial registeration This study was registered at ClinicalTrials.gov (number NCT00854828) in March 2009.
dc.identifier

10.1007/s00586-022-07200-3

dc.identifier.issn

0940-6719

dc.identifier.issn

1432-0932

dc.identifier.uri

https://hdl.handle.net/10161/28012

dc.language

eng

dc.publisher

Springer Science and Business Media LLC

dc.relation.ispartof

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

dc.relation.isversionof

10.1007/s00586-022-07200-3

dc.subject

Lumbar Vertebrae

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Animals

dc.subject

Humans

dc.subject

Kyphosis

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Lordosis

dc.subject

Scoliosis

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Postoperative Complications

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Spinal Fusion

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Retrospective Studies

dc.subject

Adult

dc.title

The impact of lumbar alignment targets on mechanical complications after adult lumbar scoliosis surgery.

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

1573

pubs.end-page

1582

pubs.issue

6

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Orthopaedic Surgery

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Neurosurgery

pubs.publication-status

Published

pubs.volume

31

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