Transfacet transforaminal lumbar interbody fusion (TF-TLIF) results in greater change in spondylolisthesis and posterior disc height compared to percutaneous TLIF (Perc-TLIF) or minimally invasive TLIF (MIS-TLIF): a retrospective study.
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2025-09
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Abstract
Background
The evolution of the transforaminal lumbar interbody fusion (TLIF) has resulted in the popularization of three main techniques: the minimally invasive TLIF (MIS-TLIF), the transfacet TLIF (TF-TLIF), and the percutaneous TLIF (Perc-TLIF). While MIS methods have previously been established as superior to open TLIF, there remains an unclear consensus on the utility and clinical outcomes associated with these different MIS techniques. This study aims to compare clinical and radiographic outcomes between the three approaches to TLIF.Methods
A retrospective analysis of the electronic medical records of a single fellowship-trained surgeon was performed for all patients receiving a single-level Perc-TLIF, MIS-TLIF, or TF-TLIF between 2018 and 2024. Variables collected included pre-operative and post-operative radiographic measures (e.g., change in spondylolisthesis, disc height, segmental lordosis), as well as clinical outcomes (e.g., length of stay, operating time, opioid utilization, readmission rates), and data were analyzed using a multivariable regression model.Results
Ninety-four total patients undergoing TLIF surgery were identified (TF-TLIF: n=17; MIS-TLIF: n=31; Perc-TLIF: n=46). In our regression model accounting for other clinical and radiographic variables, the transfacet approach was associated with greater change in spondylolisthesis (vs. MIS, P=0.03) and posterior disc height (vs. MIS, P=0.005). The percutaneous approach was associated with lower estimated blood loss (vs. MIS, P=0.004).Conclusions
Although there are limitations, the TF-TLIF shows promising results compared to MIS-TLIF and Perc-TLIF approaches, with improved spondylolisthesis reduction and posterior disc height correction.Type
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Woo, Joshua, Abdullah Wael Saleh, Andreas Seas, Alyssa M Bartlett, Chuan-Ching Huang, Eghosa Adodo, Arnav Sharma, Favour C Ononogbu-Uche, et al. (2025). Transfacet transforaminal lumbar interbody fusion (TF-TLIF) results in greater change in spondylolisthesis and posterior disc height compared to percutaneous TLIF (Perc-TLIF) or minimally invasive TLIF (MIS-TLIF): a retrospective study. Journal of spine surgery (Hong Kong), 11(3). pp. 492–504. 10.21037/jss-24-168 Retrieved from https://hdl.handle.net/10161/33498.
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Scholars@Duke
Andreas Seas
Parastou F. Quist
Courtney Rory Goodwin
Associate Professor of Neurosurgery, Radiation Oncology, Orthopedic Surgery.
Director of Spine Oncology,
Associate Residency Program Director
Third Year Study Program Director Neurosciences, Duke University School of Medicine
Director of Spine Metastasis, Duke Center for Brain and Spine Metastasis, Department of Neurosurgery
Duke Cancer Institute, Duke University Medical Center
Muhammad Abd-El-Barr
As a Neurosurgeon with fellowship training in Spine Surgery, I have dedicated my professional life to treating patients with spine disorders. These include spinal stenosis, spondylolisthesis, scoliosis, herniated discs and spine tumors. I incorporate minimally-invasive spine (MIS) techniques whenever appropriate to minimize pain and length of stay, yet not compromise on achieving the goals of surgery, which is ultimately to get you back to the quality of life you once enjoyed. I was drawn to medicine and neurosurgery for the unique ability to incorporate the latest in technology and neuroscience to making patients better. I will treat you and your loved ones with the same kind of care I would want my loved ones to be treated with. In addition to my clinical practice, I will be working with Duke Bioengineers and Neurobiologists on important basic and translational questions surrounding spinal cord injuries (SCI), which we hope to bring to clinical relevance.
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