Proximal Junctional Kyphosis Prevention in Adult Spinal Deformity Surgery: A Technical Review of Tethering and Adjunctive Strategies.
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2026-05-21
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Abstract
BACKGROUND AND OBJECTIVES: Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) remain significant complications after long-segment posterior fusion for adult spinal deformity. Preventive strategies-including tethering, vertebral cement augmentation (VCA), hooks, trajectory modifications, and alignment optimization-have been proposed, but comparative evidence remains heterogeneous. The objective of this narrative review is to synthesize current biomechanical and clinical evidence, prioritize clinically meaningful end points (revision and PJF), and differentiate them from purely radiographic PJK. METHODS: Narrative review of biomechanical and clinical studies (cadaveric, finite-element, retrospective/prospective cohorts, and meta-analyses) evaluating tethering configurations (first/second level above the upper instrumented vertebra, crosslink anchoring), hooks, VCA, screw-trajectory/multilevel sublaminar stabilization, and alignment/frailty-informed selection. Dual screening and data extraction with consensus adjudication and qualitative synthesis were performed due to heterogeneity; no new meta-analysis was conducted. RESULTS: Posterior ligamentous augmentation (sublaminar/weave tethers) demonstrates the most consistent observed reduction in PJK and PJF, with the strongest signals at second level above the upper instrumented vertebra and when combined with age-adjusted alignment and patient-risk optimization. Complications are rare but include the risk of laminar/dural injury, band elongation, and increased implant cost and learning curve. VCA mainly addresses fracture-type PJF in low bone mineral density/elderly patients with device-specific risks; hooks may soften the proximal transition but have mixed clinical results. Biomechanics support moderate tether preload and careful anchor selection; artificial intelligence risk tools remain supplementary pending external validation. Evidence quality is limited by retrospective designs, variable definitions, and short-term to mid-term follow-up. CONCLUSION: Tethering is an effective adjunct-not a stand-alone solution-best used within a multimodal strategy (bone health, frailty, and age-adjusted alignment), with selective application of hooks or VCA based on failure mode risk. Standardized, prospective multicenter studies are necessary to determine long-term durability and comparative effectiveness.
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Tahmasebpour, Paritash, Pawel P Jankowski, Jason Liang, Joshua Lin, Kyriakos D Chatzis, Peter S Tretiakov, Spencer Matthews, Louis Boissiere, et al. (2026). Proximal Junctional Kyphosis Prevention in Adult Spinal Deformity Surgery: A Technical Review of Tethering and Adjunctive Strategies. Oper Neurosurg. 10.1227/ons.0000000000002072 Retrieved from https://hdl.handle.net/10161/34695.
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Christopher Ignatius Shaffrey
I have more than 25 years of experience treating patients of all ages with spinal disorders. I have had an interest in the management of spinal disorders since starting my medical education. I performed residencies in both orthopaedic surgery and neurosurgery to gain a comprehensive understanding of the entire range of spinal disorders. My goal has been to find innovative ways to manage the range of spinal conditions, straightforward to complex. I have a focus on managing patients with complex spinal disorders. My patient evaluation and management philosophy is to provide engaged, compassionate care that focuses on providing the simplest and least aggressive treatment option for a particular condition. In many cases, non-operative treatment options exist to improve a patient’s symptoms. I have been actively engaged in clinical research to find the best ways to manage spinal disorders in order to achieve better results with fewer complications.
Peter Passias
Throughout my medical career, I have remained dedicated to improving my patients' quality of life. As a specialist in adult cervical and spinal deformity surgery, I understand the significant impact our interventions have on individuals suffering from debilitating pain and physical and mental health challenges. Spinal deformity surgery merges the complexities of spinal biomechanics with the needs of an aging population. My research focuses on spinal alignment, biomechanics, innovative surgical techniques, and health economics to ensure value-based care that enhances patient outcomes.
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