STING'ing Zika virus in neurons.

dc.contributor.author

Coyne, Carolyn B

dc.date.accessioned

2021-04-16T19:57:45Z

dc.date.available

2021-04-16T19:57:45Z

dc.date.issued

2018-09

dc.date.updated

2021-04-16T19:57:43Z

dc.description.abstract

Studies in Drosophila reveal that the insect homologue of the stimulator of interferon genes (STING) exerts antiviral activity against Zika virus infection in the fly brain through the induction of autophagy, providing key insights into the possible evolutionary function of STING in antiviral defence.

dc.identifier

10.1038/s41564-018-0232-5

dc.identifier.issn

2058-5276

dc.identifier.issn

2058-5276

dc.identifier.uri

https://hdl.handle.net/10161/22584

dc.language

eng

dc.publisher

Springer Science and Business Media LLC

dc.relation.ispartof

Nature microbiology

dc.relation.isversionof

10.1038/s41564-018-0232-5

dc.subject

Brain

dc.subject

Animals

dc.subject

Humans

dc.subject

Drosophila melanogaster

dc.subject

Disease Models, Animal

dc.subject

Drosophila Proteins

dc.subject

Membrane Proteins

dc.subject

Autophagy

dc.subject

Zika Virus

dc.subject

Zika Virus Infection

dc.title

STING'ing Zika virus in neurons.

dc.type

Journal article

duke.contributor.orcid

Coyne, Carolyn B|0000-0002-1884-6309

pubs.begin-page

975

pubs.end-page

976

pubs.issue

9

pubs.organisational-group

School of Medicine

pubs.organisational-group

Molecular Genetics and Microbiology

pubs.organisational-group

Duke

pubs.organisational-group

Basic Science Departments

pubs.publication-status

Published

pubs.volume

3

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