The health impact of adult cervical deformity in patients presenting for surgical treatment: Comparison to United States population norms and chronic disease states based on the EuroQuol-5 dimensions questionnaire

dc.contributor.author

Smith, Justin S

dc.contributor.author

Line, Breton

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Bess, Shay

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Shaffrey, Christopher I

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Kim, Han Jo

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Mundis, Gregory

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Scheer, Justin K

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Klineberg, Eric

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O'Brien, Michael

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Hostin, Richard

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Gupta, Munish

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Daniels, Alan

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Kelly, Michael

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Gum, Jeffrey L

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Schwab, Frank J

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Lafage, Virginie

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Lafage, Renaud

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Ailon, Tamir

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Passias, Peter

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Protopsaltis, Themistocles

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Albert, Todd J

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Riew, K Daniel

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Hart, Robert

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Burton, Doug

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Deviren, Vedat

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Ames, Christopher P

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Group, International Spine Study

dc.date.accessioned

2023-07-09T21:30:58Z

dc.date.available

2023-07-09T21:30:58Z

dc.date.issued

2017-05-01

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2023-07-09T21:30:57Z

dc.description.abstract

BACKGROUND: Although adult cervical spine deformity (ACSD) is associated with pain and disability, its health impact has not been quantified in comparison to other chronic diseases. OBJECTIVE: To perform a comparative analysis of the health impact of symptomatic ACSD to US normative and chronic disease values using EQ-5D (EuroQuol-5 Dimensions questionnaire) scores. METHODS: ACSD patients presenting for surgical treatment were identified from a prospectively collected multicenter database. Baseline demographics and EQ-5D scores were collected and compared with US normative and disease state values. RESULTS: Of 121 ACSD patients, 115 (95%) completed the EQ-5D (60% women, mean age 61 years, previous spine surgery in 44%). Diagnoses included kyphosis with mid-cervical (63.4%), cervico-thoracic (23.5%), or thoracic (8.7%) apex and primary coronal deformity (4.3%). The mean ACSD EQ-5D index was 0.511 (standard definition = 0.224), which is 34% below the bottom 25th percentile (0.780) for similar age- and gender-matched US normative populations. Mean ACSD EQ-5D index values were worse than the bottom 25th percentile for several other disease states, including chronic ischemic heart disease (0.708), malignant breast cancer (0.708), and malignant prostate cancer (0.708). ACSD mean index values were comparable to the bottom 25th percentile values for blindness/low vision (0.543), emphysema (0.508), renal failure (0.506), and stroke (0.463). EQ-5D scores did not significantly differ based on cervical deformity type (P =.66). CONCLUSION: The health impact of symptomatic ACSD is substantial, with negative impact across all EQ-5D domains. The mean ACSD EQ-5D index was comparable to the bottom 25th percentile values for blindness/low vision, emphysema, renal failure, and stroke.

dc.identifier.issn

0148-396X

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1524-4040

dc.identifier.uri

https://hdl.handle.net/10161/28388

dc.language

en

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Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

Clinical Neurosurgery

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10.1093/neuros/nyx028

dc.title

The health impact of adult cervical deformity in patients presenting for surgical treatment: Comparison to United States population norms and chronic disease states based on the EuroQuol-5 dimensions questionnaire

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

duke.contributor.orcid

Passias, Peter|0000-0002-1479-4070|0000-0003-2635-2226

pubs.begin-page

716

pubs.end-page

725

pubs.issue

5

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

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Neurosurgery

pubs.publication-status

Published

pubs.volume

80

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