Can a Minimal Clinically Important Difference Be Achieved in Elderly Patients with Adult Spinal Deformity Who Undergo Minimally Invasive Spinal Surgery?

dc.contributor.author

Park, Paul

dc.contributor.author

Okonkwo, David O

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Nguyen, Stacie

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Mundis, Gregory M

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Than, Khoi D

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Deviren, Vedat

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La Marca, Frank

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Fu, Kai-Ming

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Wang, Michael Y

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Uribe, Juan S

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Anand, Neel

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Fessler, Richard

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Nunley, Pierce D

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Chou, Dean

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Kanter, Adam S

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Shaffrey, Christopher I

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Akbarnia, Behrooz A

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Passias, Peter G

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Eastlack, Robert K

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Mummaneni, Praveen V

dc.contributor.author

International Spine Study Group

dc.date.accessioned

2023-07-20T15:26:07Z

dc.date.available

2023-07-20T15:26:07Z

dc.date.issued

2016-02

dc.date.updated

2023-07-20T15:25:21Z

dc.description.abstract

Background

Older age has been considered a relative contraindication to complex spinal procedures. Minimally invasive surgery (MIS) techniques to treat patients with adult spinal deformity (ASD) have emerged with the potential benefit of decreased approach-related morbidity.

Objective

To determine whether a minimal clinically important difference (MCID) could be achieved in patients ages ≥ 65 years with ASD who underwent MIS.

Methods

Multicenter database of patients who underwent MIS for ASD was queried. Outcome metrics assessed were Oswestry Disability Index (ODI) and visual analog scale (VAS) scores for back and leg pain. On the basis of published reports, MCID was defined as a positive change of 12.8 ODI, 1.2 VAS back pain, and 1.6 VAS leg pain.

Results

Forty-two patients were identified. Mean age was 70.3 years; 31 (73.8%) were women. Preoperatively, mean coronal curve, pelvic tilt, pelvic incidence to lumbar lordosis mismatch, and sagittal vertical axis were 35°, 24.6°, 14.2°, and 4.7 cm, respectively. Postoperatively, mean coronal curve, pelvic tilt, pelvic incidence to lumbar lordosis, and sagittal vertical axis were 18°, 25.4°, 11.9°, and 4.9 cm, respectively. A mean of 5.0 levels was treated posteriorly, and a mean of 4.0 interbody fusions was performed. Mean ODI improved from 47.1 to 25.1. Mean VAS back and leg pain scores improved from 6.8 and 5.9 to 2.7 and 2.7, respectively. Mean follow-up was 32.1 months. For ODI, 64.3% of patients achieved MCID. For VAS back and leg pain, 82.9% and 72.2%, respectively, reached MCID.

Conclusions

MCID represents the threshold at which patients feel a meaningful clinical improvement has occurred. Our study results suggest that the majority of elderly patients with modest ASD can achieve MCID with MIS.
dc.identifier

S1878-8750(15)01239-5

dc.identifier.issn

1878-8750

dc.identifier.issn

1878-8769

dc.identifier.uri

https://hdl.handle.net/10161/28477

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

World neurosurgery

dc.relation.isversionof

10.1016/j.wneu.2015.09.072

dc.subject

International Spine Study Group

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Lumbar Vertebrae

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Sacrum

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Humans

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Spinal Curvatures

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Back Pain

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Radiography

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Treatment Outcome

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Spinal Fusion

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Cohort Studies

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Age Factors

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Recovery of Function

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Databases, Factual

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Aged

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Female

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Male

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Minimally Invasive Surgical Procedures

dc.title

Can a Minimal Clinically Important Difference Be Achieved in Elderly Patients with Adult Spinal Deformity Who Undergo Minimally Invasive Spinal Surgery?

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

duke.contributor.orcid

Passias, Peter G|0000-0002-1479-4070|0000-0003-2635-2226

pubs.begin-page

168

pubs.end-page

172

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

pubs.volume

86

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