Use of multiple rods and proximal junctional kyphosis in adult spinal deformity surgery.

dc.contributor.author

Ye, Jichao

dc.contributor.author

Gupta, Sachin

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Farooqi, Ali S

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Yin, Tsung-Cheng

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Soroceanu, Alex

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Schwab, Frank J

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Lafage, Virginie

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Kelly, Michael P

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Kebaish, Khaled

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Hostin, Richard

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Gum, Jeffrey L

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Smith, Justin S

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Shaffrey, Christopher I

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Scheer, Justin K

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Protopsaltis, Themistocles S

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Passias, Peter G

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Klineberg, Eric O

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Kim, Han Jo

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Hart, Robert A

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Hamilton, D Kojo

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Ames, Christopher P

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Gupta, Munish C

dc.date.accessioned

2023-07-08T12:20:35Z

dc.date.available

2023-07-08T12:20:35Z

dc.date.issued

2023-06

dc.date.updated

2023-07-08T12:20:34Z

dc.description.abstract

Objective

Multiple rods are utilized in adult spinal deformity (ASD) surgery to increase construct stiffness. However, the impact of multiple rods on proximal junctional kyphosis (PJK) is not well established. This study aimed to investigate the impact of multiple rods on PJK incidence in ASD patients.

Methods

ASD patients from a prospective multicenter database with a minimum follow-up of 1 year were retrospectively reviewed. Clinical and radiographic data were collected preoperatively, at 6 weeks postoperatively, at 6 months postoperatively, at 1 year postoperatively, and at every subsequent year postoperatively. PJK was defined as a kyphotic increase of > 10° in the Cobb angle from the upper instrumented vertebra (UIV) to UIV+2 as compared with preoperative values. Demographic data, radiographic parameters, and PJK incidence were compared between the multirod and dual-rod patient cohorts. PJK-free survival analysis was performed using Cox regression to control for demographic characteristics, comorbidities, level of fusion, and radiographic parameters.

Results

Overall, 307/1300 (23.62%) cases utilized multiple rods. Cases with multiple rods were more likely to be revisions (68.4% vs 46.5%, p < 0.001), to be posterior only (80.7% vs 61.5%, p < 0.001), involve more levels of fusion (mean 11.73 vs 10.60, p < 0.001), and include 3-column osteotomy (42.9% vs 17.1%, p < 0.001). Patients with multiple rods also had greater preoperative pelvic retroversion (mean pelvic tilt 27.95° vs 23.58°, p < 0.001), greater thoracolumbar junction kyphosis (-15.9° vs -11.9°, p = 0.001), and more severe sagittal malalignment (C7-S1 sagittal vertical axis 99.76 mm vs 62.23 mm, p < 0.001), all of which corrected postoperatively. Patients with multiple rods had similar incidence rates of PJK (58.6% vs 58.1%) and revision surgery (13.0% vs 17.7%). The PJK-free survival analysis demonstrated equivalent PJK-free survival durations among the patients with multiple rods (HR 0.889, 95% CI 0.745-1.062, p = 0.195) after controlling for demographic and radiographic parameters. Further stratification based on implant metal type demonstrated noninferior PJK incidence rates with multiple rods in the titanium (57.1% vs 54.6%, p = 0.858), cobalt chrome (60.5% vs 58.7%, p = 0.646), and stainless steel (20% vs 63.7%, p = 0.008) cohorts.

Conclusions

Multirod constructs for ASD are most frequently utilized in revision, long-level reconstructions with 3-column osteotomy. The use of multiple rods in ASD surgery does not result in an increased incidence of PJK and is not affected by rod metal type.
dc.identifier.issn

1547-5654

dc.identifier.issn

1547-5646

dc.identifier.uri

https://hdl.handle.net/10161/28323

dc.language

eng

dc.publisher

Journal of Neurosurgery Publishing Group (JNSPG)

dc.relation.ispartof

Journal of neurosurgery. Spine

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10.3171/2023.4.spine23209

dc.subject

ASD

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PJK

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adult spinal deformity

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lumbar

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multicenter

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multiple rods

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osteotomy

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proximal junctional kyphosis

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reconstruction

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thoracic

dc.subject

thoracolumbar

dc.title

Use of multiple rods and proximal junctional kyphosis in adult spinal deformity surgery.

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

duke.contributor.orcid

Passias, Peter G|0000-0002-1479-4070|0000-0003-2635-2226

pubs.begin-page

1

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9

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

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