Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements.

dc.contributor.author

Liu, Y

dc.contributor.author

Murphy, SK

dc.contributor.author

Murtha, AP

dc.contributor.author

Fuemmeler, BF

dc.contributor.author

Schildkraut, J

dc.contributor.author

Huang, Z

dc.contributor.author

Overcash, F

dc.contributor.author

Kurtzberg, J

dc.contributor.author

Jirtle, R

dc.contributor.author

Iversen, ES

dc.contributor.author

Forman, MR

dc.contributor.author

Hoyo, C

dc.date.accessioned

2022-03-23T19:36:46Z

dc.date.available

2022-03-23T19:36:46Z

dc.date.issued

2012-07

dc.date.updated

2022-03-23T19:36:45Z

dc.description.abstract

Depressed mood in pregnancy has been linked to low birth weight (LBW, 4,500 g) infants had 5.9% higher methylation at the PLAGL1 DMR compared with normal birth weight infants. Our findings confirm that severe maternal depressed mood in pregnancy is associated with LBW, and that MEG3 and IGF2 plasticity may play important roles.

dc.identifier

20734

dc.identifier.issn

1559-2308

dc.identifier.issn

1559-2308

dc.identifier.uri

https://hdl.handle.net/10161/24661

dc.language

English

dc.publisher

Informa UK Limited

dc.relation.ispartof

Epigenetics : official journal of the DNA Methylation Society

dc.relation.isversionof

10.4161/epi.20734

dc.subject

Humans

dc.subject

Pregnancy Complications

dc.subject

Birth Weight

dc.subject

Insulin-Like Growth Factor II

dc.subject

Cell Cycle Proteins

dc.subject

Tumor Suppressor Proteins

dc.subject

Transcription Factors

dc.subject

RNA, Untranslated

dc.subject

Sequence Analysis, DNA

dc.subject

Depression

dc.subject

DNA Methylation

dc.subject

Genomic Imprinting

dc.subject

Pregnancy

dc.subject

Adolescent

dc.subject

Adult

dc.subject

Infant, Newborn

dc.subject

Female

dc.subject

Male

dc.subject

Genetic Loci

dc.subject

High-Throughput Nucleotide Sequencing

dc.subject

RNA, Long Noncoding

dc.title

Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements.

dc.type

Journal article

duke.contributor.orcid

Murphy, SK|0000-0001-8298-7272

duke.contributor.orcid

Kurtzberg, J|0000-0002-3370-0703

pubs.begin-page

735

pubs.end-page

746

pubs.issue

7

pubs.organisational-group

Duke

pubs.organisational-group

Nicholas School of the Environment

pubs.organisational-group

School of Medicine

pubs.organisational-group

Trinity College of Arts & Sciences

pubs.organisational-group

Faculty

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Family Medicine and Community Health

pubs.organisational-group

Pathology

pubs.organisational-group

Pediatrics

pubs.organisational-group

Family Medicine and Community Health, Prevention Research

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Statistical Science

pubs.organisational-group

Environmental Sciences and Policy

pubs.organisational-group

Institutes and Provost's Academic Units

pubs.organisational-group

Initiatives

pubs.organisational-group

Duke Innovation & Entrepreneurship

pubs.organisational-group

Pediatrics, Transplant and Cellular Therapy

pubs.publication-status

Published

pubs.volume

7

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
p255 Liu.pdf
Size:
981.99 KB
Format:
Adobe Portable Document Format
Description:
Published version