B-cell targeting in chronic Graft-versus-Host disease.

dc.contributor.author

Zeiser, Robert

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Sarantopoulos, Stefanie

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Blazar, Bruce R

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United States

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2018-03-01T14:10:55Z

dc.date.available

2018-03-01T14:10:55Z

dc.date.issued

2018-02-01

dc.description.abstract

Over the last decade our understanding of the pathophysiology of chronic graft-versus-host disease (cGVHD) has improved considerably. In this spotlight, we discuss emerging insights into the pathophysiology of cGVHD with a focus on B-cells. First, we summarize supporting evidence derived from mouse and human studies. Next, novel cGVHD therapy approaches that target B-cells will be covered to provide treating physicians with an overview of the rationale behind the emerging armamentarium against cGVHD.

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https://www.ncbi.nlm.nih.gov/pubmed/29437591

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blood-2017-11-784017

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1528-0020

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https://hdl.handle.net/10161/16092

dc.language

eng

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American Society of Hematology

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Blood

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10.1182/blood-2017-11-784017

dc.title

B-cell targeting in chronic Graft-versus-Host disease.

dc.type

Journal article

pubs.author-url

https://www.ncbi.nlm.nih.gov/pubmed/29437591

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Basic Science Departments

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Duke

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Duke Cancer Institute

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Immunology

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Institutes and Centers

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School of Medicine

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Published online

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