B-cell targeting in chronic Graft-versus-Host disease.
dc.contributor.author | Zeiser, Robert | |
dc.contributor.author | Sarantopoulos, Stefanie | |
dc.contributor.author | Blazar, Bruce R | |
dc.coverage.spatial | United States | |
dc.date.accessioned | 2018-03-01T14:10:55Z | |
dc.date.available | 2018-03-01T14:10:55Z | |
dc.date.issued | 2018-02-01 | |
dc.description.abstract | Over the last decade our understanding of the pathophysiology of chronic graft-versus-host disease (cGVHD) has improved considerably. In this spotlight, we discuss emerging insights into the pathophysiology of cGVHD with a focus on B-cells. First, we summarize supporting evidence derived from mouse and human studies. Next, novel cGVHD therapy approaches that target B-cells will be covered to provide treating physicians with an overview of the rationale behind the emerging armamentarium against cGVHD. | |
dc.identifier | ||
dc.identifier | blood-2017-11-784017 | |
dc.identifier.eissn | 1528-0020 | |
dc.identifier.uri | ||
dc.language | eng | |
dc.publisher | American Society of Hematology | |
dc.relation.ispartof | Blood | |
dc.relation.isversionof | 10.1182/blood-2017-11-784017 | |
dc.title | B-cell targeting in chronic Graft-versus-Host disease. | |
dc.type | Journal article | |
pubs.author-url | ||
pubs.organisational-group | Basic Science Departments | |
pubs.organisational-group | Duke | |
pubs.organisational-group | Duke Cancer Institute | |
pubs.organisational-group | Immunology | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | School of Medicine | |
pubs.publication-status | Published online |
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