Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention.

dc.contributor.author

Passias, Peter G

dc.contributor.author

Ahmad, Waleed

dc.contributor.author

Kummer, Nicholas

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Lafage, Renaud

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Lafage, Virginie

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Kebaish, Khaled

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Daniels, Alan

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Klineberg, Eric

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Soroceanu, Alex

dc.contributor.author

Gum, Jeffrey

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Line, Breton

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Hart, Robert

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Burton, Douglas

dc.contributor.author

Eastlack, Robert

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Jain, Amit

dc.contributor.author

Smith, Justin S

dc.contributor.author

Ames, Christopher P

dc.contributor.author

Shaffrey, Christopher

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Schwab, Frank

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Hostin, Richard

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Bess, Shay

dc.contributor.author

International Spine Study Group***

dc.date.accessioned

2023-06-16T15:23:28Z

dc.date.available

2023-06-16T15:23:28Z

dc.date.issued

2022-01

dc.date.updated

2023-06-16T15:23:28Z

dc.description.abstract

Background

With increasing interest in cost optimization, costs of adult spinal deformity (ASD) surgery intersections with frailty merit investigation.

Objective

To investigate costs associated with ASD and frailty.

Methods

Patients with ASD (scoliosis ≥20°, sagittal vertical axis [SVA] ≥5 cm, pelvic tilt ≥ 25°, or thoracic kyphosis ≥ 60°) with baseline and 2-yr radiographic data were included. Patients were severely frail (SF), frail (F), or not frail (NF). Utility data were converted from Oswestry Disability Index to Short-Form Six-Dimension. Quality-adjusted life years (QALYs) used 3% rate for decline to life expectancy. Costs were calculated using PearlDiver. Loss of work costs were based on SRS-22rQ9 and US Bureau of Labor Statistics. Accounting for complications, length of stay, revisions, and death, cost per QALY at 2 yr and life expectancy were calculated.

Results

Five hundred ninety-two patients with ASD were included (59.8 ± 14.0 yr, 80% F, body mass index: 27.7 ± 6.0 kg/m2, Adult Spinal Deformity-Frailty Index: 3.3 ± 1.6, and Charlson Comorbidity Index: 1.8 ± 1.7). The average blood loss was 1569.3 mL, and the operative time was 376.6 min, with 63% undergoing osteotomy and 54% decompression. 69.3% had a posterior-only approach, 30% combined, and 0.7% anterior-only. 4.7% were SF, 22.3% F, and 73.0% NF. At baseline, 104 were unemployed losing $971.38 weekly. After 1 yr, 62 remained unemployed losing $50 508.64 yearly. With propensity score matching for baseline SVA, cost of ASD surgery at 2 yr for F/SF was greater than that for NF ($81 347 vs $69 722). Cost per QALY was higher for F/SF at 2 yr than that for NF ($436 473 vs $430 437). At life expectancy, cost per QALY differences became comparable ($58 965 vs $58 149).

Conclusion

Despite greater initial cost, F and SF patients show greater improvement. Cost per QALY for NF and F patients becomes similar at life expectancy.
dc.identifier

00006123-202201000-00017

dc.identifier.issn

0148-396X

dc.identifier.issn

1524-4040

dc.identifier.uri

https://hdl.handle.net/10161/28054

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

Neurosurgery

dc.relation.isversionof

10.1227/neu.0000000000001756

dc.subject

International Spine Study Group***

dc.subject

Humans

dc.subject

Kyphosis

dc.subject

Retrospective Studies

dc.subject

Quality of Life

dc.subject

Adult

dc.subject

Frailty

dc.subject

Financial Stress

dc.title

Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention.

dc.type

Journal article

duke.contributor.orcid

Passias, Peter G|0000-0002-1479-4070|0000-0003-2635-2226

duke.contributor.orcid

Shaffrey, Christopher|0000-0001-9760-8386

pubs.begin-page

148

pubs.end-page

153

pubs.issue

1

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

pubs.volume

90

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