Self-Regulation and Psychopathology: Toward an Integrative Translational Research Paradigm.

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Date

2017-05

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Abstract

This article presents a general framework in which different manifestations of psychopathology can be conceptualized as dysfunctions in one or more mechanisms of self-regulation, defined as the ongoing process of managing personal goal pursuit in the face of internal, interpersonal, and environmental forces that would derail it. The framework is based on the assertion that self-regulation is a critical locus for the proximal influence on motivation, cognition, emotion, and behavior of more distal factors such as genetics, temperament, socialization history, and neurophysiology. Psychological theories of self-regulation are ideal platforms from which to integrate the study of self-regulation both within and across traditional disciplines. This article has two related goals: to elucidate how the construct of self-regulation provides a unique conceptual platform for the study of psychopathology and to illustrate that platform by presenting our research on depression as an example.

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Humans, Psychological Theory, Depressive Disorder, Psychiatry, Self-Control, Translational Research, Biomedical

Citation

Published Version (Please cite this version)

10.1146/annurev-clinpsy-032816-045012

Publication Info

Strauman, Timothy J (2017). Self-Regulation and Psychopathology: Toward an Integrative Translational Research Paradigm. Annual review of clinical psychology, 13(1). pp. 497–523. 10.1146/annurev-clinpsy-032816-045012 Retrieved from https://hdl.handle.net/10161/31191.

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Scholars@Duke

Strauman

Timothy J. Strauman

Professor of Psychology and Neuroscience

Professor Strauman’s work is grounded in the premise that mental health and well-being are fundamentally shaped by self-regulation—how individuals pursue goals, respond to challenges, and adapt over time. His research integrates clinical psychology, affective neuroscience, and behavioral science to characterize the psychological and neurobiological systems that support self-regulation, and to understand how disruptions in these systems contribute to vulnerability to depression and related conditions.

Across a program of experimental, clinical, and neuroimaging research, his work has examined self-regulation as a multi-level system, including its cognitive and motivational mechanisms, its development through socialization, and its links to affective and immunological processes. This work has also informed the development and evaluation of novel interventions targeting self-regulatory dysfunction.

More recently, his work has focused on translating this science of self-regulation into scalable approaches to intervention and prevention. This includes the development of new models of treatment that target regulatory processes across disorders, as well as efforts to extend effective self-regulation skills beyond traditional clinical settings and into everyday contexts. This translational focus reflects a broader aim of building integrated, system-level approaches to mental health that can improve outcomes at population scale.


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