Crosstalk rejection in full-field optical coherence tomography using spatially incoherent illumination with a partially coherent source

dc.contributor.author

Dhalla, Al-Hafeez

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Migacz, Justin V

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Izatt, Joseph A

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Izatt, JA

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Fujimoto, JG

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Tuchin, VV

dc.date.accessioned

2011-06-21T17:27:41Z

dc.date.issued

2010-05-03

dc.description.abstract

The recent advent of ultra high frame rate cameras gives rise to the possibility of constructing swept source full-field OCT systems with achievable volume rates approaching 10Hz and net A-scan rates approaching 10MHz. Unfortunately, when illuminated with partially coherent light, full-field OCT in turbid media suffers resolution and SNR degradation from coherent multiple scattering, a phenomenon commonly referred to as crosstalk. As a result, most FFOCT systems employ thermal sources, which provide spatially incoherent illumination to achieve crosstalk rejection. However, these thermal sources preclude the use of swept source lasers. In this work, we demonstrate the use of a carefully configured FFOCT system employing multimode fiber in the illumination arm to reduce the spatial coherence of a partially coherent source. By reducing the coherence area below the system resolution, the illumination becomes effectively spatially incoherent and crosstalk is largely rejected. We compare FFOCT images of a USAF test chart positioned beneath both transparent and turbid phantoms using both illumination schemes. © 2010 Copyright SPIE - The International Society for Optical Engineering.

dc.description.version

Version of Record

dc.identifier.issn

1605-7422

dc.identifier.uri

https://hdl.handle.net/10161/4221

dc.language.iso

en_US

dc.publisher

SPIE-INT SOC OPTICAL ENGINEERING

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Progress in Biomedical Optics and Imaging - Proceedings of SPIE

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10.1117/12.843391

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Optics Letters

dc.title

Crosstalk rejection in full-field optical coherence tomography using spatially incoherent illumination with a partially coherent source

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dc.type

Journal article

duke.contributor.orcid

Izatt, Joseph A|0000-0003-1993-2249

duke.date.pubdate

2010-7-1

duke.description.issue

13

duke.description.volume

35

pubs.begin-page

2305

pubs.end-page

2307

pubs.organisational-group

Biomedical Engineering

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Clinical Science Departments

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Duke

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Duke Institute for Brain Sciences

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Institutes and Provost's Academic Units

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Ophthalmology

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Pratt School of Engineering

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School of Medicine

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University Institutes and Centers

pubs.publication-status

Published

pubs.volume

7554

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