Human Fetal Tissue Regulation. Impact on Pediatric and Adult Respiratory-related Research.






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Publication Info

Al Alam, Denise, Philip L Ballard, Claude Jourdan Le Saux, Jennifer L Ingram, Thomas J Mariani, Nuala S Moore, Daniel J Weiss, Michelle Yu, et al. (2021). Human Fetal Tissue Regulation. Impact on Pediatric and Adult Respiratory-related Research. Annals of the American Thoracic Society, 18(2). pp. 204–208. 10.1513/annalsats.202005-460ps Retrieved from

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Jennifer Leigh Ingram

Associate Professor in Medicine

Dr. Ingram's research interests focus on the study of airway remodeling in human asthma. Proliferation, migration, and invasion of airway fibroblasts are key features of airway remodeling that contribute to diminished lung function over time. Dr. Ingram uses molecular biology approaches to define the effects of interleukin-13 (IL-13), a cytokine abundantly produced in the asthmatic airway, in the human airway fibroblast. She has identified important regulatory functions of several proteins prevalent in asthma that control fibroblast growth and pro-fibrotic growth factor production in response to IL-13. By understanding these pathways and their role in human asthma and the chronic effects of airway remodeling, novel treatment strategies may be developed.

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