Task Group 174 Report: Utilization of [¹⁸ F]Fluorodeoxyglucose Positron Emission Tomography ([¹⁸ F]FDG-PET) in Radiation Therapy.

Das, Shiva K

McGurk, Ross

Miften, Moyed

Mutic, Sasa

Bowsher, James

Bayouth, John

Erdi, Yusuf

Mawlawi, Osama

Boellaard, Ronald

Bowen, Stephen R

Xing, Lei

Bradley, Jeffrey

Schoder, Heiko

Yin, Fang-Fang

Sullivan, Daniel C

Kinahan, Paul

2021-04-01T21:57:24Z

2021-04-01T21:57:24Z

2019-10

2021-04-01T21:57:23Z

The use of positron emission tomography (PET) in radiation therapy (RT) is rapidly increasing in the areas of staging, segmentation, treatment planning, and response assessment. The most common radiotracer is ¹⁸ F-fluorodeoxyglucose ([¹⁸ F]FDG), a glucose analog with demonstrated efficacy in cancer diagnosis and staging. However, diagnosis and RT planning are different endeavors with unique requirements, and very little literature is available for guiding physicists and clinicians in the utilization of [¹⁸ F]FDG-PET in RT. The two goals of this report are to educate and provide recommendations. The report provides background and education on current PET imaging systems, PET tracers, intensity quantification, and current utilization in RT (staging, segmentation, image registration, treatment planning, and therapy response assessment). Recommendations are provided on acceptance testing, annual and monthly quality assurance, scanning protocols to ensure consistency between interpatient scans and intrapatient longitudinal scans, reporting of patient and scan parameters in literature, requirements for incorporation of [¹⁸ F]FDG-PET in treatment planning systems, and image registration. The recommendations provided here are minimum requirements and are not meant to cover all aspects of the use of [¹⁸ F]FDG-PET for RT.

0094-2405

2473-4209

https://hdl.handle.net/10161/22517

eng

Wiley

Medical physics

10.1002/mp.13676

Humans

Radioactive Tracers

Fluorodeoxyglucose F18

Positron-Emission Tomography

Neoplasm Staging

Treatment Outcome

Radiotherapy

Radiotherapy Planning, Computer-Assisted

Biological Transport

Quality Control

Image Processing, Computer-Assisted

Respiratory-Gated Imaging Techniques

Research Report

Task Group 174 Report: Utilization of [¹⁸ F]Fluorodeoxyglucose Positron Emission Tomography ([¹⁸ F]FDG-PET) in Radiation Therapy.

Journal article

Yin, Fang-Fang|0000-0002-2025-4740|0000-0003-1064-2149

Sullivan, Daniel C|0000-0002-7556-5650

e706

e725

10

School of Medicine

Duke Clinical Research Institute

Radiology

Duke

Institutes and Centers

Clinical Science Departments

Duke Kunshan University Faculty

Duke Cancer Institute

Radiation Oncology

Duke Kunshan University

Published

46