Docetaxel Resistance in Prostate Cancer: Taking It Up a Notch.
| dc.contributor.author | Zhang, Tian | |
| dc.contributor.author | Armstrong, Andrew J | |
| dc.coverage.spatial | United States | |
| dc.date.accessioned | 2015-11-20T21:02:23Z | |
| dc.date.issued | 2015-10-15 | |
| dc.description.abstract | Notch signaling is implicated in prostate cancer progression and docetaxel resistance. Cui and colleagues describe the additive efficacy and mechanisms of a γ-secretase inhibitor, PF-03084014, and docetaxel in preclinical models of prostate cancer, suggesting the need for further clinical development of Notch pathway modulators in men with metastatic prostate cancer. | |
| dc.identifier | ||
| dc.identifier | 1078-0432.CCR-15-1613 | |
| dc.identifier.issn | 1078-0432 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | American Association for Cancer Research (AACR) | |
| dc.relation.ispartof | Clin Cancer Res | |
| dc.relation.isversionof | 10.1158/1078-0432.CCR-15-1613 | |
| dc.subject | Amyloid Precursor Protein Secretases | |
| dc.subject | Animals | |
| dc.subject | Antineoplastic Combined Chemotherapy Protocols | |
| dc.subject | Humans | |
| dc.subject | Male | |
| dc.subject | Prostatic Neoplasms | |
| dc.title | Docetaxel Resistance in Prostate Cancer: Taking It Up a Notch. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Zhang, Tian|0000-0001-8914-3531 | |
| duke.contributor.orcid | Armstrong, Andrew J|0000-0001-7012-1754 | |
| pubs.author-url | ||
| pubs.begin-page | 4505 | |
| pubs.end-page | 4507 | |
| pubs.issue | 20 | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Medicine, Medical Oncology | |
| pubs.organisational-group | Pharmacology & Cancer Biology | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Surgery | |
| pubs.organisational-group | Surgery, Vascular Surgery | |
| pubs.publication-status | Published | |
| pubs.volume | 21 |