Comparative Analysis of Gene Regulation in Single Cells Using Compass

Abstract

Department

Description

Provenance

Subjects

single-cell, gene regulation, multi-omics

Citation

Scholars@Duke

Chen

Ming Chen

Associate Professor of Pathology

Our laboratory is interested in understanding the molecular and genetic events underlying cancer progression and metastasis. The focus of our work is a series of genetically engineered mouse models that faithfully recapitulate human disease. Using a combination of mouse genetics, omics technologies, cross-species analyses and in vitro approaches, we aim to identify cancer cell–intrinsic and –extrinsic mechanisms driving metastatic cancer progression, with a long–term goal of developing new therapeutic strategies for preventing and treating metastatic disease. 

Ji

Zhicheng Ji

Assistant Professor of Biostatistics & Bioinformatics

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