Management of adolescents and adults with febrile illness in resource limited areas

Loading...
Thumbnail Image

Date

2011

Journal Title

Journal ISSN

Volume Title

Repository Usage Stats

264
views
372
downloads

Citation Stats

Abstract

Overlap in the clinical features of febrile illnesses and limited laboratory services make the management of febrile patients in resource limited settings challenging. WHO guidelines for managing febrile adolescents and adults in resource limited settings are available for first level health facilities and are forthcoming for district hospitals. First level health facility guidelines recommend antimalarials for those with a positive malaria diagnostic test, antibacterials for those with signs of severe illness or specific bacterial infections, and hospital referral of those with severe illness or no apparent diagnosis. Management guidelines should be validated, locally adapted, and improved on the basis of local or national surveillance data and sentinel hospital studies. Malaria, tuberculosis, and HIV diagnostic tests can enhance management by ruling out a specific illness or by directing towards a particular diagnosis. Clinical trials of empirical treatment strategies and advocacy for better clinical laboratory services could help improve management guidelines and patient outcomes.

Department

Description

Provenance

Subjects

Citation

Crump, J. A., S. Gove, et al. (2011). "Management of adolescents and adults with febrile illness in resource limited areas." BMJ 343.

Published Version (Please cite this version)

10.1136/bmj.d4847

Publication Info

Crump, John A, Sandy Gove and Christopher M Parry (2011). Management of adolescents and adults with febrile illness in resource limited areas. 10.1136/bmj.d4847 Retrieved from https://hdl.handle.net/10161/5949.

This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.

Scholars@Duke

Crump

John Andrew Crump

Adjunct Professor in the Department of Medicine

I am based in northern Tanzania where I am Site Leader for Duke University’s collaborative research program based at Kilimanjaro Christian Medical Centre and Director of Tanzania Operations for the Duke Global Health Institute. I oversee the design and implementation of research studies on infectious diseases, particularly febrile illness, invasive bacterial disease, HIV-associated opportunistic infections, clinical trials of antiretroviral therapy and prevention of mother-to-child transmission of HIV, and infectious diseases diagnostics. In addition, I am a medical epidemiologist with the US Centers for Disease Control and Prevention (CDC). My CDC work focuses on enteric infection epidemiology and prevention in developing countries, particularly invasive salmonelloses.


Unless otherwise indicated, scholarly articles published by Duke faculty members are made available here with a CC-BY-NC (Creative Commons Attribution Non-Commercial) license, as enabled by the Duke Open Access Policy. If you wish to use the materials in ways not already permitted under CC-BY-NC, please consult the copyright owner. Other materials are made available here through the author’s grant of a non-exclusive license to make their work openly accessible.