The Impact of Worsening Heart Failure in the United States.

dc.contributor.author

Cooper, Lauren B

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DeVore, Adam D

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Michael Felker, G

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United States

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2015-12-03T17:31:11Z

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2015-10

dc.description.abstract

In-hospital worsening heart failure represents a clinical scenario wherein a patient hospitalized for acute heart failure experiences a worsening of their condition, requiring escalation of therapy. Worsening heart failure is associated with worse in-hospital and postdischarge outcomes. Worsening heart failure is increasingly being used as an endpoint or combined endpoint in clinical trials, as it is unique to episodes of acute heart failure and captures an important event during the inpatient course. While prediction models have been developed to identify worsening heart failure, there are no known FDA-approved medications associated with decreased worsening heart failure. Continued study is warranted.

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/26462100

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S1551-7136(15)00057-4

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1551-7136

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https://hdl.handle.net/10161/11002

dc.language

eng

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Elsevier BV

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Heart Fail Clin

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10.1016/j.hfc.2015.07.004

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Clinical trials

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Medications

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Outcomes

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Worsening heart failure

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Acute Disease

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Clinical Trials as Topic

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Heart Failure

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Hospitalization

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Humans

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Incidence

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Registries

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United States

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The Impact of Worsening Heart Failure in the United States.

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Journal article

duke.contributor.orcid

DeVore, Adam D|0000-0002-4679-2221

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/26462100

pubs.begin-page

603

pubs.end-page

614

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4

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Clinical Science Departments

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Duke

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Duke Clinical Research Institute

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Institutes and Centers

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Medicine

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Medicine, Cardiology

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School of Medicine

pubs.publication-status

Published

pubs.volume

11

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