Patient-Reported Outcomes After Complex Adult Spinal Deformity Surgery: 5-Year Results of the Scoli-Risk-1 Study.
| dc.contributor.author | Zuckerman, Scott L | |
| dc.contributor.author | Cerpa, Meghan | |
| dc.contributor.author | Lenke, Lawrence G | |
| dc.contributor.author | Shaffrey, Christopher I | |
| dc.contributor.author | Carreon, Leah Y | |
| dc.contributor.author | Cheung, Kenneth MC | |
| dc.contributor.author | Kelly, Michael P | |
| dc.contributor.author | Fehlings, Michael G | |
| dc.contributor.author | Ames, Christopher P | |
| dc.contributor.author | Boachie-Adjei, Oheneba | |
| dc.contributor.author | Dekutoski, Mark B | |
| dc.contributor.author | Kabeaish, Khaled M | |
| dc.contributor.author | Lewis, Stephen J | |
| dc.contributor.author | Matsuyama, Yukihiro | |
| dc.contributor.author | Pellisé, Ferran | |
| dc.contributor.author | Qiu, Yong | |
| dc.contributor.author | Schwab, Frank J | |
| dc.contributor.author | Smith, Justin S | |
| dc.contributor.author | AO Spine Knowledge Forum Deformity and SRS Scoli-RISK-1 Study Group | |
| dc.date.accessioned | 2023-06-15T17:08:42Z | |
| dc.date.available | 2023-06-15T17:08:42Z | |
| dc.date.issued | 2022-10 | |
| dc.date.updated | 2023-06-15T17:08:40Z | |
| dc.description.abstract | Study designProspective cohort.ObjectiveTo prospectively evaluate PROs up to 5-years after complex ASD surgery.MethodsThe Scoli-RISK-1 study enrolled 272 ASD patients undergoing surgery from 15 centers. Inclusion criteria was Cobb angle of >80°, corrective osteotomy for congenital or revision deformity, and/or 3-column osteotomy. The following PROs were measured prospectively at intervals up to 5-years postoperative: ODI, SF36-PCS/MCS, SRS-22, NRS back/leg. Among patients with 5-year follow-up, comparisons were made from both baseline and 2-years postoperative to 5-years postoperative. PROs were analyzed using mixed models for repeated measures.ResultsSeventy-seven patients (28.3%) had 5-year follow-up data. Comparing baseline to 5-year data among these 77 patients, significant improvement was seen in all PROs: ODI (45.2 vs. 29.3, P < 0.001), SF36-PCS (31.5 vs. 38.8, P < 0.001), SF36-MCS (44.9 vs. 49.1, P = 0.009), SRS-22-total (2.78 vs. 3.61, P < 0.001), NRS-back pain (5.70 vs. 2.95, P < 0.001) and NRS leg pain (3.64 vs. 2.62, P = 0.017). In the 2 to 5-year follow-up period, no significant changes were seen in any PROs. The percentage of patients achieving MCID from baseline to 5-years were: ODI (62.0%) and the SRS-22r domains of function (70.4%), pain (63.0%), mental health (37.5%), self-image (60.3%), and total (60.3%). Surprisingly, mean values (P > 0.05) and proportion achieving MCID did not differ significantly in patients with major surgery-related complications compared to those without.ConclusionsAfter complex ASD surgery, significant improvement in PROs were seen at 5-years postoperative in ODI, SF36-PCS/MCS, SRS-22r, and NRS-back/leg pain. No significant changes in PROs occurred during the 2 to 5-year postoperative period. Those with major surgery-related complications had similar PROs and proportion of patients achieving MCID as those without these complications. | |
| dc.identifier.issn | 2192-5682 | |
| dc.identifier.issn | 2192-5690 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | SAGE Publications | |
| dc.relation.ispartof | Global spine journal | |
| dc.relation.isversionof | 10.1177/2192568220988276 | |
| dc.subject | AO Spine Knowledge Forum Deformity and SRS Scoli-RISK-1 Study Group | |
| dc.title | Patient-Reported Outcomes After Complex Adult Spinal Deformity Surgery: 5-Year Results of the Scoli-Risk-1 Study. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Shaffrey, Christopher I|0000-0001-9760-8386 | |
| pubs.begin-page | 1736 | |
| pubs.end-page | 1744 | |
| pubs.issue | 8 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Orthopaedic Surgery | |
| pubs.organisational-group | Neurosurgery | |
| pubs.publication-status | Published | |
| pubs.volume | 12 |
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