Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia.
| dc.contributor.author | Blalock, Dan V | |
| dc.contributor.author | Bosworth, Hayden B | |
| dc.contributor.author | Reeve, Bryce B | |
| dc.contributor.author | Voils, Corrine I | |
| dc.date.accessioned | 2024-01-26T00:02:02Z | |
| dc.date.available | 2024-01-26T00:02:02Z | |
| dc.date.issued | 2019-04 | |
| dc.description.abstract | Medication nonadherence is a significant clinical problem among individuals taking statins. Poor adherence is often attributable to several reasons, yet most adherence interventions target a single reason. Baseline data were examined from a randomized clinical trial of 236 patients with hyperlipidemia. A latent class analysis was then performed on patients reporting any nonadherence (n = 109). A 4-class solution provided the most optimal fit and differentiation of classes. Class 1 (N = 59, 54%) included patients who reported occasionally forgetting. Class 2 (N = 16, 14%) represented patients who were concerned about side effects. Class 3 (N = 17, 16%) represented patients who reported out-of-routine life events as contributing to nonadherence. Class 4 (N = 17, 16%) represented patients who endorsed a large number reasons indiscriminately. Class membership was almost uniformly unrelated to any patient demographic factors or treatment arm. Each cluster of reasons defining these patients may be best addressed through different intervention strategies. | |
| dc.identifier | 10.1007/s10865-018-9954-3 | |
| dc.identifier.issn | 0160-7715 | |
| dc.identifier.issn | 1573-3521 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Springer Science and Business Media LLC | |
| dc.relation.ispartof | Journal of behavioral medicine | |
| dc.relation.isversionof | 10.1007/s10865-018-9954-3 | |
| dc.rights.uri | ||
| dc.subject | Humans | |
| dc.subject | Hydroxymethylglutaryl-CoA Reductase Inhibitors | |
| dc.subject | Cross-Sectional Studies | |
| dc.subject | Aged | |
| dc.subject | Middle Aged | |
| dc.subject | Female | |
| dc.subject | Male | |
| dc.subject | Hyperlipidemias | |
| dc.subject | Medication Adherence | |
| dc.title | Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Blalock, Dan V|0000-0002-8349-9825 | |
| duke.contributor.orcid | Bosworth, Hayden B|0000-0001-6188-9825 | |
| duke.contributor.orcid | Reeve, Bryce B|0000-0002-6709-8714 | |
| pubs.begin-page | 291 | |
| pubs.end-page | 299 | |
| pubs.issue | 2 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Faculty | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Pediatrics | |
| pubs.organisational-group | Psychiatry & Behavioral Sciences | |
| pubs.organisational-group | Medicine, General Internal Medicine | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Duke Clinical Research Institute | |
| pubs.organisational-group | Institutes and Provost's Academic Units | |
| pubs.organisational-group | Center for the Study of Aging and Human Development | |
| pubs.organisational-group | Initiatives | |
| pubs.organisational-group | Duke Science & Society | |
| pubs.organisational-group | Population Health Sciences | |
| pubs.organisational-group | Duke Innovation & Entrepreneurship | |
| pubs.organisational-group | Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences | |
| pubs.organisational-group | Duke - Margolis Center For Health Policy | |
| pubs.publication-status | Published | |
| pubs.volume | 42 |