The prevalence and clinical significance of inhalant withdrawal symptoms among a national sample.

Perron, Brian E

Glass, Joseph E

Ahmedani, Brian K

Vaughn, Michael G

Roberts, Daniel E

Wu, Li-Tzy

New Zealand

2015-12-03T17:38:32Z

2011-04

BACKGROUND: Inhalants are among the most common and dangerous forms of substance use, but very little research on inhalant use disorders exist. Unlike other substances, the Diagnostic and Statistical Manual, 4th edition (DSM-IV) indicates that inhalants do not have an associated withdrawal syndrome among persons who meet criteria for inhalant dependence. METHODS: Using data from the National Epidemiologic Survey on Alcohol and Related Conditions, this study examines the prevalence of withdrawal symptoms among inhalant users. Prevalence of inhalant withdrawal symptoms for inhalants was also compared with the prevalence of cocaine withdrawal symptoms to help determine the presence of an inhalant withdrawal syndrome. RESULTS: Approximately 47.8% of persons who met criteria for inhalant dependence reported experiencing three or more inhalant-related withdrawal symptoms that were clinically significant. Among those with inhalant dependence, almost half of the withdrawal symptoms were as common as the corresponding withdrawal symptoms experienced by persons with cocaine dependence. Furthermore, the percentage of persons with inhalant dependence reporting clinically significant inhalant withdrawal symptoms was almost equal to the percentage of persons with cocaine dependence reporting clinically significant cocaine withdrawal symptoms. CONCLUSIONS: These data provide evidence for an inhalant-related withdrawal syndrome among persons with inhalant dependence. Revisions to DSM-IV should consider including inhalant withdrawal as a diagnostic criterion for this disorder.

http://www.ncbi.nlm.nih.gov/pubmed/21709745

https://hdl.handle.net/10161/11014

eng

Informa UK Limited

Subst Abuse Rehabil

10.2147/SAR.S14937

The prevalence and clinical significance of inhalant withdrawal symptoms among a national sample.

Journal article

Wu, Li-Tzy|0000-0002-5909-2259

http://www.ncbi.nlm.nih.gov/pubmed/21709745

69

76

2

Center for Child and Family Policy

Clinical Science Departments

Duke

Duke Clinical Research Institute

Duke Institute for Brain Sciences

Institutes and Centers

Institutes and Provost's Academic Units

Medicine

Medicine, General Internal Medicine

Psychiatry & Behavioral Sciences

Psychiatry & Behavioral Sciences, Social and Community Psychiatry

Sanford School of Public Policy

School of Medicine

University Institutes and Centers

Published

2011