Cell and extracellular matrix growth theory and its implications for tumorigenesis.

Dr. Ehsan Samei, PhD, DABR, FAAPM, FSPIE, FAIMBE, FIOMP, FACR is a Persian-American medical physicist. He is the Reed and Martha Rice Distinguished Professor of Radiology, and Professor of Medical Physics, Biomedical Engineering, Physics, and Electrical and Computer Engineering at Duke University. He serves as the Chief Imaging Physicist for Duke University Health System, the Director of the Carl E Ravin Advanced Imaging Laboratories and the Center for Virtual Imaging Trials (CVIT), and co-PI of one the five Centers of Excellence in Regulatory Science and Innovation (CERSI), Triangle CERSI. He is certified by the American Board of Radiology, recognized as a Distinguished Investigator by the Academy of Radiology Research, and awarded Fellow by five professional organization. He founded/co-founded the Duke Medical Physics Program, the Duke Imaging Physics Residency Program, the Duke Clinical Imaging Physics Group, the Center for Virtual Imaging Trials, and the Society of Directors of Academic Medical Physics Programs (SDAMPP). He has held senior leadership positions in the AAPM, SPIE, SDAMPP, and RSNA, including election to the presidency of the SEAAPM (2010-2011), SDAMPP (2011), and AAPM (2023).

Dr. Samei's scientific expertise include x-ray imaging, theoretical imaging models, simulation methods, and experimental techniques in medical image formation, quantification, and perception. His research aims to bridge the gap between scientific scholarship and clinical practice, in the meaningful realization of translational research, and in clinical processes that are informed by scientific evidence. He has advanced image quality and safety metrics and radiometrics that are clinically relevant and that can be used to design, optimize, and monitor interpretive and quantitative performance of imaging techniques. These have been implemented in advanced imaging performance characterization, procedural optimization, and clinical dose and quality analytics. His most recent research interests have been virtual clinical trial across a broad spectrum of oncologic, pulmonary, cardiac, and vascular diseases, and developing methodological advances that provide smart fusions of principle-informed and AI-based, data-informed approaches to scientific inquiry.

Dr. Samei has mentored over 140 trainees (graduate and postgraduate). He has more than 1400 scientific publications including more than 360 referred journal articles, 600 conference presentations, and 4 books. Citations to his work is reflected in an h-index of 74 and a Weighted Relative Citation Ratio of 613. His laboratory of over 20 researchers has been supported continuously over two decades by 44 extramural grants, culminating in a NIH Program Project grant in 2021 to establish the national Center for Virtual Imaging Trials (CVIT), joining a small number of prominent Biomedical Technology Research Centers across the nation. In 2023, he, along with 3 other PIs, was awarded to lead one of five national Centers of Excellence in Regulatory Science and Innovation (Triangle CERSI) by the FDA.

Professor Bejan was awarded the Benjamin Franklin Medal 2018 and the Humboldt Research Award 2019. His research covers engineering science and applied physics: thermodynamics, heat transfer, convection, design, and evolution in nature.

He is ranked among the top 0.01% of the most cited and impactful world scientists (and top 10 in Engineering world wide) in the 2019 citations impact database created by Stanford University’s John Ioannidis, in PLoS Biology.  He is the author of 30 books and 700 peer-referred articles. His h-index is 111 with 92,000 citations on Google Scholar. He received 18 honorary doctorates from universities in 11 countries.