Call to action: Understanding the differences in the use of SGLT-2 inhibitors and GLP-1 receptor agonists.

dc.contributor.author

Khedagi, Apurva

dc.contributor.author

Hoke, Cara

dc.contributor.author

Kelsey, Michelle

dc.contributor.author

Coviello, Andrea

dc.contributor.author

Jones, W Schuyler

dc.contributor.author

Jackson, Larry R

dc.contributor.author

Patel, Manesh R

dc.contributor.author

McGarrah, Rob W

dc.contributor.author

Pagidipati, Neha J

dc.contributor.author

Shah, Nishant P

dc.date.accessioned

2023-04-04T03:00:02Z

dc.date.available

2023-04-04T03:00:02Z

dc.date.issued

2023-03

dc.date.updated

2023-04-04T03:00:00Z

dc.description.abstract

Cardiovascular disease remains one of the most prominent global health problems and has been demonstrated to disproportionally affect certain communities. Despite an increasing collective effort to improve health inequalities, a multitude of disparities continue to affect cardiovascular outcomes. Among the most prominent disparities within cardiovascular disease prevention are with the use and distribution of sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists. Several landmark trials have demonstrated the efficacy of these novel agents, not only in cardiovascular disease prevention among those with diabetes, but also in heart failure and chronic kidney disease. However, the use of these agents remains limited by disparities in certain racial/ethnic, sex, and socioeconomic groups. This review works to highlight and understand these differences on the use and prescribing patterns of pivotal agents in cardiovascular disease prevention, SGLT-2 inhibitors and GLP-1 agonists. Our aim is to enrich understanding and to inspire efforts to end disparities in cardiovascular morbidity and mortality due to race, sex and income inequality.

dc.identifier

S2666-6677(23)00019-3

dc.identifier.issn

2666-6677

dc.identifier.issn

2666-6677

dc.identifier.uri

https://hdl.handle.net/10161/26997

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

American journal of preventive cardiology

dc.relation.isversionof

10.1016/j.ajpc.2023.100477

dc.subject

Disparities

dc.subject

GLP1-RA

dc.subject

Health equity

dc.subject

Prevention

dc.subject

SGLT2i

dc.title

Call to action: Understanding the differences in the use of SGLT-2 inhibitors and GLP-1 receptor agonists.

dc.type

Journal article

duke.contributor.orcid

Jones, W Schuyler|0000-0002-7288-9596

duke.contributor.orcid

Jackson, Larry R|0000-0002-0195-1081

duke.contributor.orcid

Patel, Manesh R|0000-0001-6477-9728

duke.contributor.orcid

Shah, Nishant P|0000-0002-2666-7132

pubs.begin-page

100477

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Medicine

pubs.organisational-group

Medicine, Cardiology

pubs.organisational-group

Duke Clinical Research Institute

pubs.publication-status

Published

pubs.volume

13

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Call to action Understanding the differences in the use of SGLT-2 inhibitors and GLP-1 receptor agonists.pdf
Size:
1.08 MB
Format:
Adobe Portable Document Format