A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma

dc.contributor.author

Khasraw, Mustafa

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Singh, Kirit

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Violette, Marlene

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Corcoran, Anna

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Rlethen, Emily

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Hotchkiss, Kelly

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Railton, Chelsea

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Blethen, Kathryn

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Thomas, Elizabeth

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Ashley, David

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Desjardins, Annick

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Friedman, Henry

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Johnson, Margaret O

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Friedman, Allan

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Keir, Stephen

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Buckley, Evan

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Herndon, James

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McLendon, Roger

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Sampson, John

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Calabrese, Evan

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Lopez, Giselle

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Grant, Gerald

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Patel, Anoop

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Gregory, Simon

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Li, Chuan-Yuan

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Fecci, Peter

dc.date.accessioned

2026-04-02T17:11:11Z

dc.date.available

2026-04-02T17:11:11Z

dc.date.issued

2025-01-22

dc.identifier.uri

https://hdl.handle.net/10161/34367

dc.relation.ispartof

Research Square

dc.relation.isversionof

10.21203/rs.3.rs-5822396/v1

dc.rights.uri

https://creativecommons.org/licenses/by-nc/4.0

dc.title

A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma

dc.type

Journal article

duke.contributor.orcid

Khasraw, Mustafa|0000-0003-3249-9849

duke.contributor.orcid

Friedman, Henry|0000-0001-7588-032X

duke.contributor.orcid

Johnson, Margaret O|0000-0003-1208-622X|0009-0005-5596-3407

duke.contributor.orcid

McLendon, Roger|0000-0001-6682-4588

duke.contributor.orcid

Grant, Gerald|0000-0002-2651-4603

duke.contributor.orcid

Gregory, Simon|0000-0002-7805-1743

pubs.edition

Version 1

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Duke

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School of Medicine

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Basic Science Departments

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Clinical Science Departments

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Institutes and Centers

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Integrative Immunobiology

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Molecular Genetics and Microbiology

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Neurobiology

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Pharmacology & Cancer Biology

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Medicine

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Pathology

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Pediatrics

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Medicine, Medical Oncology

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Pediatrics, Hematology-Oncology

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Duke Cancer Institute

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University Institutes and Centers

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Duke Institute for Brain Sciences

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Duke Molecular Physiology Institute

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Neurology

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Neurology, General & Community Neurology

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Neurosurgery

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Neurosurgery, Neuro-Oncology

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Neurosurgery

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