An Early Stage Researcher's Primer on Systems Medicine Terminology.

Abstract

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references. Results: This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic.

Department

Description

Provenance

Subjects

multiscale data science, multiscale modeling, systems medicine

Citation

Published Version (Please cite this version)

10.1089/nsm.2020.0003

Publication Info

Zanin, Massimiliano, Nadim AA Aitya, José Basilio, Jan Baumbach, Arriel Benis, Chandan K Behera, Magda Bucholc, Filippo Castiglione, et al. (2021). An Early Stage Researcher's Primer on Systems Medicine Terminology. Network and systems medicine, 4(1). pp. 2–50. 10.1089/nsm.2020.0003 Retrieved from https://hdl.handle.net/10161/33079.

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Scholars@Duke

Benis

Arriel Benis

Adjunct Associate Professor in the Department of Biomedical Engineering

Dr. Arriel Benis is a researcher and educator working at the intersection of medical informatics, digital health, and artificial intelligence, advancing health systems and biomedical engineering innovation. His work leverages AI, data science, and knowledge management to improve health-related decision-making at the individual, population, and public health levels.

His research focuses on developing data-driven healthcare solutions that enhance patient care, optimize clinical processes, and promote sustainable systems. Dr. Benis has engineered (a) clinical decision support systems with direct patient and healthcare partitioners impact such as ADHD, PTSD, and diabetes patient management and health communication, (b) MIMO -the Medical Informatics and Digital Health Multilingual Ontology- integrating more than 3500 terms and concepts across 30+ languages, actively deployed in healthcare organizations for AI-powered training and international projects support, (c) smart home and smart city health monitoring approach from a One Health viewpoint. Dr. Benis is a pioneer of the One Digital Health framework, which strategically links digital health innovation with environmental monitoring.

His past academic positions include serving as a department head and track director in biomedical and health informatics. He holds various leadership roles in the international medical informatics community, is a fellow of the International Academy for Health Sciences Informatics, and is the Editor-in-Chief of JMIR Medical Informatics. Dr. Benis is committed to training the next generation of innovators in digital health and medical informatics.


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