Comparison of PROMIS scores after total hip and total ankle arthroplasty : a propensity score-matched study.
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2025-05
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This study evaluated joint-specific and generic patient-reported outcome measures (PROMs) after total hip arthroplasty (THA) and total ankle arthroplasty (TAA) in matched cohorts, while evaluating implant survivorship and 90-day hospital use.Methods
Primary THA and TAA patients from 1 January 2015 to 1 January 2023 with minimum one-year follow-up were retrospectively reviewed. After applying exclusion criteria, 2,092 THAs and 478 TAAs were analyzed. Demographics, pre- and postoperative PROMs, revision surgeries, emergency department visits, and readmissions were collected. THA and TAA patients were then propensity score matched at a 2:1 ratio for age, sex, race, BMI, American Society of Anesthesiologists classification, and comorbidities, resulting in a final cohort of 844 THAs and 455 TAAs for comparison.Results
Median preoperative Patient-Reported Outcomes Measurement Information System (PROMIS) pain interference (PI) scores between THA and TAA were calculated (66.0 (IQR 62.0 to 70.0) vs 65.0 (IQR 62.0 to 70.0); p = 0.276), and both showed improvement at six weeks. However, THA patients exhibited lower median PROMIS PI scores at one year (53.0 vs 54.0; p = 0.009), as well as a greater median decrease in PROMIS PI from preoperative to one year (-13.0 (IQR -20.0 to -8.0) vs -12.0 (IQR -18.0 to -7.0); p = 0.023). Median preoperative PROMIS physical function (PF) was worse in THA patients (36.0 (IQR 32.0 to 40.0) vs 37.0 (IQR 33.0 to 40.0); p = 0.031), but showed greater median improvement compared to TAA patients at both six weeks (7.0 (IQR 3.0 to 12.0) vs 3.0 (IQR -2.0 to 9.0); p < 0.001) and one year (11.0 (IQR 6.0 to 17.0) vs 8.0 (IQR 4.5 to 13.0); p < 0.001). Preoperative PROMIS depression scores were similar and improved similarly in both groups. Joint-specific PROMs improved in both cohorts.Conclusion
Patients undergoing THA or TAA experienced improvements in joint-specific PROMs postoperatively which translated to improved generic PROMs across both joints. Generic PROMs can be a useful tool to compare outcomes in THA and TAA. Results suggest that higher functional scores may be achieved sooner in THA.Type
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Leal, Justin, Christopher T Holland, Mark E Easley, James A Nunley, Sean P Ryan, Michael P Bolognesi, Samuel S Wellman, William A Jiranek, et al. (2025). Comparison of PROMIS scores after total hip and total ankle arthroplasty : a propensity score-matched study. Bone & joint open, 6(5 Supple A). pp. 1–13. 10.1302/2633-1462.65.bjo-2024-0200.r1 Retrieved from https://hdl.handle.net/10161/34697.
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Scholars@Duke
Mark Erik Easley
James Albert Nunley
My current research interests are both clinical and basic science. Currently, in the Orthopaedic Research Laboratory, we are investigating the biomechanical properties of the deltoid ligament in the ankle. This is a clinically relevant problem and we will hopefully identify ways to improve the correction of the adult relaxed flat foot. We are also performing a preliminary investigation into the blood supply of the distal tibia to look for a vascularized bone transfer.
We have recently completed a biomechanical study looking at the strength of fixation for proximal metatarsal osteotomies in the correction of hallux valgus and that information has been submitted for publication.
Clinical projects have looked into nerve palsies after total elbow replacement and to reconstructive upper and lower extremity surgery.
Sean Ryan
Dr. Sean Ryan is an Adult Reconstruction surgeon in the Division of Orthopaedic Surgery. He specializes in hip and knee primary and revision arthroplasty as well as periacetabular osteotomies for hip dysplasia. His research interests include patient outcomes, implant survivorship, implant design, periprosthetic joint infection, and instability.
Michael Paul Bolognesi
As chief of the adult reconstruction service, the majority of my research effort has been directed toward clinical outcomes, implant survivorship, functional recovery, the biology of hip and knee arthritis and cost effectiveness.
Samuel S. Wellman
My career has primarily focused on clinical care of hip and knee arthritis. I run a busy Adult Reconstruction (hip and knee replacement) practice. I am also Chief of the Orthopedic Surgery service at the Durham VA medical center. In these roles, I work daily with orthopedic residents, and train them to manage these issues both non-operatively and with surgery. I also mentor residents, fellows,and medical students on their research projects, typically in collaboration with my clinical partner, Michael Bolognesi, MD. We often have multiple residents working on a variety of projects at once. My research interests lie mainly with clinical research in hip and knee replacement, including biomechanical studies, outcomes research, and clinical trials. I have also begun collaborating with basic science colleagues on biomarker research
William Arthur Jiranek
I am an Orthopaedic physician and work in Adult Reconstructive Orthopaedics, predominantly with hip and knee replacement surgeries. I also help manage revision surgeries and take care of people with infections or fractures around their implants. I am interested in the whole continuum of care for arthritis and not just the surgical treatment of it. Even though I specialize in surgery, not everyone needs that treatment, and as an Orthopaedic doctor, my role is to help direct the whole process.
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