Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.

dc.contributor.author

Passias, Peter G

dc.contributor.author

Williamson, Tyler K

dc.contributor.author

Mir, Jamshaid M

dc.contributor.author

Smith, Justin S

dc.contributor.author

Lafage, Virginie

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Lafage, Renaud

dc.contributor.author

Line, Breton

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Daniels, Alan H

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Gum, Jeffrey L

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Schoenfeld, Andrew J

dc.contributor.author

Hamilton, David Kojo

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Soroceanu, Alex

dc.contributor.author

Scheer, Justin K

dc.contributor.author

Eastlack, Robert

dc.contributor.author

Mundis, Gregory M

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Diebo, Bassel

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Kebaish, Khaled M

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Hostin, Richard A

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Gupta, Munish C

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Kim, Han Jo

dc.contributor.author

Klineberg, Eric O

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Ames, Christopher P

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Hart, Robert A

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Burton, Douglas C

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Schwab, Frank J

dc.contributor.author

Shaffrey, Christopher I

dc.contributor.author

Bess, Shay

dc.contributor.author

On Behalf Of The International Spine Study Group

dc.date.accessioned

2023-10-11T18:07:16Z

dc.date.available

2023-10-11T18:07:16Z

dc.date.issued

2023-08

dc.date.updated

2023-10-11T18:07:14Z

dc.description.abstract

Background

While reimbursement is centered on 90-day outcomes, many patients may still achieve optimal, long-term outcomes following adult spinal deformity (ASD) surgery despite transient short-term complications.

Objective

Compare long-term clinical success and cost-utility between patients achieving optimal realignment and suboptimally aligned peers.

Study design/setting

Retrospective cohort study of a prospectively collected multicenter database.

Methods

ASD patients with two-year (2Y) data included. Groups were propensity score matched (PSM) for age, frailty, body mass index (BMI), Charlson Comorbidity Index (CCI), and baseline deformity. Optimal radiographic criteria are defined as meeting low deformity in all three (Scoliosis Research Society) SRS-Schwab parameters or being proportioned in Global Alignment and Proportionality (GAP). Cost-per-QALY was calculated for each time point. Multivariable logistic regression analysis and ANCOVA (analysis of covariance) adjusting for baseline disability and deformity (pelvic incidence (PI), pelvic incidence minus lumbar lordosis (PI-LL)) were used to determine the significance of surgical details, complications, clinical outcomes, and cost-utility.

Results

A total of 930 patients were considered. Following PSM, 253 "optimal" (O) and 253 "not optimal" (NO) patients were assessed. The O group underwent more invasive procedures and had more levels fused. Analysis of complications by two years showed that the O group suffered less overall major (38% vs. 52%, p = 0.021) and major mechanical complications (12% vs. 22%, p = 0.002), and less reoperations (23% vs. 33%, p = 0.008). Adjusted analysis revealed O patients more often met MCID (minimal clinically important difference) in SF-36 PCS, SRS-22 Pain, and Appearance. Cost-utility-adjusted analysis determined that the O group generated better cost-utility by one year and maintained lower overall cost and costs per QALY (both p < 0.001) at two years.

Conclusions

Fewer late complications (mechanical and reoperations) are seen in optimally aligned patients, leading to better long-term cost-utility overall. Therefore, the current focus on avoiding short-term complications may be counterproductive, as achieving optimal surgical correction is critical for long-term success.
dc.identifier

jcm12175565

dc.identifier.issn

2077-0383

dc.identifier.issn

2077-0383

dc.identifier.uri

https://hdl.handle.net/10161/29225

dc.language

eng

dc.publisher

MDPI AG

dc.relation.ispartof

Journal of clinical medicine

dc.relation.isversionof

10.3390/jcm12175565

dc.subject

Medicare

dc.subject

adult spinal deformity

dc.subject

clinical improvement

dc.subject

complex realignment

dc.subject

complications

dc.subject

cost-utility

dc.title

Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.

dc.type

Journal article

duke.contributor.orcid

Passias, Peter G|0000-0002-1479-4070|0000-0002-9019-3285|0000-0003-2635-2226

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

5565

pubs.issue

17

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

pubs.volume

12

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