Validation of the Finnish Version of the Unified Dyskinesia Rating Scale.

dc.contributor.author

Kaasinen, Valtteri

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Scheperjans, Filip

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Kärppä, Mikko

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Korpela, Jaana

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Brück, Anna

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Sipilä, Jussi OT

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Joutsa, Juho

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Järvelä, Juha

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Eerola-Rautio, Johanna

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Martikainen, Mika H

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Airaksinen, Katja

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Stebbins, Glenn T

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Martinez-Martin, Pablo

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Goetz, Christopher G

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Lin, Jeffrey

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Luo, Sheng

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Pekkonen, Eero

dc.date.accessioned

2021-08-01T13:19:26Z

dc.date.available

2021-08-01T13:19:26Z

dc.date.issued

2021-07-14

dc.date.updated

2021-08-01T13:19:26Z

dc.description.abstract

Introduction

The Unified Dyskinesia Rating Scale (UDysRS) was developed to provide a comprehensive rating tool of dyskinesia in Parkinson's disease (PD). Because dyskinesia therapy trials involve multicenter studies, having a scale that is validated in multiple non-English languages is pivotal to international efforts to treat dyskinesia. The aim of the present study was to organize and perform an independent validation of the UDysRS Finnish version.

Methods

The UDysRS was translated into Finnish and then back-translated into English using 2 independent teams. Cognitive pretesting was conducted on the Finnish version and required modifications to the structure or wording of the translation. The final Finnish version was administered to 250 PD patients whose native language is Finnish. The data were analyzed to assess the confirmatory factor structure to the Spanish UDysRS (the reference standard). Secondary analyses included an exploratory factor analysis (EFA), independent of the reference standard.

Results

The comparative fit index (CFI), in comparison with the reference standard factor structure, was 0.963 for Finnish. In the EFA, where variability from sample to sample is expected, isolated item differences of factor structure were found between the Finnish and Reference Standard versions of the UDysRS. These subtle differences may relate to differences in sample composition or variations in disease status.

Conclusion

The overall factor structure of the Finnish version was consistent with that of the reference standard, and it can be designated as the official version of the UDysRS for Finnish speaking populations.
dc.identifier

000517369

dc.identifier.issn

0014-3022

dc.identifier.issn

1421-9913

dc.identifier.uri

https://hdl.handle.net/10161/23472

dc.language

eng

dc.publisher

S. Karger AG

dc.relation.ispartof

European neurology

dc.relation.isversionof

10.1159/000517369

dc.subject

Dyskinesia

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Parkinson’s disease

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Unified dyskinesia rating scale

dc.title

Validation of the Finnish Version of the Unified Dyskinesia Rating Scale.

dc.type

Journal article

duke.contributor.orcid

Luo, Sheng|0000-0003-4214-5809

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1

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6

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School of Medicine

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Duke Clinical Research Institute

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Biostatistics & Bioinformatics

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Duke

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Institutes and Centers

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Basic Science Departments

pubs.publication-status

Published

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