Promoting developmental transcription.

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2010-01

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Abstract

Animal growth and development depend on the precise control of gene expression at the level of transcription. A central role in the regulation of developmental transcription is attributed to transcription factors that bind DNA enhancer elements, which are often located far from gene transcription start sites. Here, we review recent studies that have uncovered significant regulatory functions in developmental transcription for the TFIID basal transcription factors and for the DNA core promoter elements that are located close to transcription start sites.

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10.1242/dev.035493

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Ohler, Uwe, and David A Wassarman (2010). Promoting developmental transcription. Development, 137(1). pp. 15–26. 10.1242/dev.035493 Retrieved from https://hdl.handle.net/10161/4172.

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Ohler

Uwe Ohler

Adjunct Associate Professor in the Department of Biostatistics & Bioinformatics

Computational Biology of Gene Regulation
Sequence Analysis
Image Expression Analysis
Applied Machine Learning


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