Promoting developmental transcription.

dc.contributor.author

Ohler, Uwe

dc.contributor.author

Wassarman, David A

dc.coverage.spatial

England

dc.date.accessioned

2011-06-21T17:27:30Z

dc.date.issued

2010-01

dc.description.abstract

Animal growth and development depend on the precise control of gene expression at the level of transcription. A central role in the regulation of developmental transcription is attributed to transcription factors that bind DNA enhancer elements, which are often located far from gene transcription start sites. Here, we review recent studies that have uncovered significant regulatory functions in developmental transcription for the TFIID basal transcription factors and for the DNA core promoter elements that are located close to transcription start sites.

dc.description.version

Version of Record

dc.identifier

https://www.ncbi.nlm.nih.gov/pubmed/20023156

dc.identifier

137/1/15

dc.identifier.eissn

1477-9129

dc.identifier.uri

https://hdl.handle.net/10161/4172

dc.language

eng

dc.language.iso

en_US

dc.publisher

The Company of Biologists

dc.relation.ispartof

Development

dc.relation.isversionof

10.1242/dev.035493

dc.relation.journal

Development

dc.subject

Animals

dc.subject

Gene Expression Regulation, Developmental

dc.subject

Humans

dc.subject

Models, Biological

dc.subject

Promoter Regions, Genetic

dc.subject

Transcription Factor TFIID

dc.subject

Transcription Initiation Site

dc.subject

Transcription, Genetic

dc.title

Promoting developmental transcription.

dc.title.alternative
dc.type

Journal article

duke.date.pubdate

2010-1-1

duke.description.issue

1

duke.description.volume

137

pubs.author-url

https://www.ncbi.nlm.nih.gov/pubmed/20023156

pubs.begin-page

15

pubs.end-page

26

pubs.issue

1

pubs.organisational-group

Basic Science Departments

pubs.organisational-group

Biostatistics & Bioinformatics

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.publication-status

Published

pubs.volume

137

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