Improved delineation of short cortical association fibers and gray/white matter boundary using whole-brain three-dimensional diffusion tensor imaging at submillimeter spatial resolution.

dc.contributor.author

Song, Allen W

dc.contributor.author

Chang, Hing-Chiu

dc.contributor.author

Petty, Christopher

dc.contributor.author

Guidon, Arnaud

dc.contributor.author

Chen, Nan-Kuei

dc.coverage.spatial

United States

dc.date.accessioned

2015-02-03T04:47:57Z

dc.date.issued

2014-11

dc.description.abstract

Recent emergence of human connectome imaging has led to a high demand on angular and spatial resolutions for diffusion magnetic resonance imaging (MRI). While there have been significant growths in high angular resolution diffusion imaging, the improvement in spatial resolution is still limited due to a number of technical challenges, such as the low signal-to-noise ratio and high motion artifacts. As a result, the benefit of a high spatial resolution in the whole-brain connectome imaging has not been fully evaluated in vivo. In this brief report, the impact of spatial resolution was assessed in a newly acquired whole-brain three-dimensional diffusion tensor imaging data set with an isotropic spatial resolution of 0.85 mm. It was found that the delineation of short cortical association fibers is drastically improved as well as the definition of fiber pathway endings into the gray/white matter boundary-both of which will help construct a more accurate structural map of the human brain connectome.

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/25264168

dc.identifier.eissn

2158-0022

dc.identifier.uri

https://hdl.handle.net/10161/9461

dc.language

eng

dc.publisher

Mary Ann Liebert Inc

dc.relation.ispartof

Brain Connect

dc.relation.isversionof

10.1089/brain.2014.0270

dc.subject

DTI

dc.subject

brain

dc.subject

connectome

dc.subject

high resolution

dc.subject

short cortical association fibers

dc.subject

Brain

dc.subject

Brain Mapping

dc.subject

Connectome

dc.subject

Diffusion Tensor Imaging

dc.subject

Gray Matter

dc.subject

Humans

dc.subject

Imaging, Three-Dimensional

dc.subject

Nerve Fibers, Myelinated

dc.subject

White Matter

dc.title

Improved delineation of short cortical association fibers and gray/white matter boundary using whole-brain three-dimensional diffusion tensor imaging at submillimeter spatial resolution.

dc.type

Journal article

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/25264168

pubs.begin-page

636

pubs.end-page

640

pubs.issue

9

pubs.organisational-group

Basic Science Departments

pubs.organisational-group

Biomedical Engineering

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Duke

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Duke Institute for Brain Sciences

pubs.organisational-group

Duke-UNC Center for Brain Imaging and Analysis

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Institutes and Provost's Academic Units

pubs.organisational-group

Neurobiology

pubs.organisational-group

Pratt School of Engineering

pubs.organisational-group

Psychiatry & Behavioral Sciences

pubs.organisational-group

Radiology

pubs.organisational-group

School of Medicine

pubs.organisational-group

University Institutes and Centers

pubs.publication-status

Published

pubs.volume

4

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
published.pdf
Size:
668.13 KB
Format:
Adobe Portable Document Format
Description:
Published version